Department of Radiology, Alfred Hospital, Melbourne, Victoria, Australia.
Monash University, Clayton, Victoria, Australia.
J Med Imaging Radiat Oncol. 2020 Jun;64(3):326-330. doi: 10.1111/1754-9485.13030. Epub 2020 Apr 3.
A single-phase dual-bolus CT (DB-CT) simultaneously opacifies both arterial and venous systems and can be utilised in the trauma setting to aid in the diagnosis of active bleeding while also allowing for optimal assessment of the abdominal and pelvic viscera. Active bleeding can be venous or arterial, the latter being amenable to angiography and potentially embolisation. We aimed to establish the accuracy of single-phase DB-CT vs commonly performed portal venous CT (PV-CT) in the diagnosis of active bleeding when compared to formal digital subtraction angiography as the gold standard.
All patients diagnosed with active bleeding on PV-CT or DB-CT at a level 1 tertiary centre over a 6-year period and who subsequently proceeded to digital subtraction angiography (DSA) were included for analysis. The initial CT images were retrospectively reviewed by two consultant interventional radiologists who were blinded to the subsequent outcome of the DSA and to each other's results. The sensitivity, specificity and inter-observer agreement between the two readers was then able to be assessed.
A total of 60 patients were included in the analysis. Sensitivity for the diagnosis for any active bleeding was high for both DB-CT and PV-CT (range 88.9%-100%) while diagnosis of specifically arterial bleeding was comparatively lower (51.9%-79%). Inter-observer agreement for the identification of arterial bleeding was better for DB-CT (fair) compared to PV-CT (poor).
Both PV-CT and DB-CT demonstrate high sensitivity in the diagnosis of any active bleeding though identification of specifically arterial bleeding is lower for both scanning methods. Nevertheless, inter-observer reliability for the identification of arterial bleeding is higher for DB-CT. Multi-phase arterial and venous CT may yield better results and could be a focus for future studies.
单相双期 CT(DB-CT)可同时使动脉和静脉系统显影,可用于创伤环境中,以帮助诊断活动性出血,同时还可以对腹部和盆腔内脏器进行最佳评估。活动性出血可分为静脉性或动脉性,后者适合进行血管造影并可能进行栓塞治疗。我们旨在确定单相 DB-CT 与常规门静脉 CT(PV-CT)在诊断活动性出血方面的准确性,将正式数字减影血管造影(DSA)作为金标准。
在 6 年期间,对在一级三级中心通过 PV-CT 或 DB-CT 诊断为活动性出血的所有患者进行了回顾性分析,这些患者随后接受了数字减影血管造影(DSA)。两名顾问介入放射科医师对初始 CT 图像进行了回顾性分析,他们对 DSA 的后续结果以及彼此的结果均不知情。然后,评估了两位读者之间的敏感性、特异性和观察者间一致性。
共纳入 60 例患者进行分析。DB-CT 和 PV-CT 对任何活动性出血的诊断均具有较高的敏感性(范围为 88.9%-100%),而动脉性出血的诊断相对较低(51.9%-79%)。DB-CT 对动脉性出血的识别具有较好的观察者间一致性(中等),而 PV-CT 则较差(差)。
PV-CT 和 DB-CT 在诊断任何活动性出血方面均具有较高的敏感性,尽管两种扫描方法对动脉性出血的识别率较低。然而,DB-CT 对动脉性出血的识别具有更高的观察者间可靠性。多期动脉和静脉 CT 可能会产生更好的结果,可能是未来研究的重点。