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当前多米诺肝移植的最新进展。

Current update in domino liver transplantation.

机构信息

Hepato-Biliary-Pancreatic and Transplantation Center/ Curry Cabral Hospital, Lisbońs Central Hospitals and University Center, and NOVA Medical School, Lisboa, Portugal.

Hepato-Biliary-Pancreatic and Transplantation Center/ Curry Cabral Hospital, Lisbońs Central Hospitals and University Center, and NOVA Medical School, Lisboa, Portugal.

出版信息

Int J Surg. 2020 Oct;82S:163-168. doi: 10.1016/j.ijsu.2020.03.017. Epub 2020 Mar 31.

Abstract

Orthotopic liver transplantation is an established treatment for end stage liver diseases as well as for some severe metabolic disorders. With increasing number of patients on the waiting list and the ongoing shortage of livers available, domino liver transplantation (DLT) became an option to further expand the organ donor pool. DLT utilizes the explanted liver of one liver transplant recipient as a donor graft in another patient. Despite being a surgically, and logistically demanding procedure, excellent results could be achieved in experienced high-volume transplant centers. In this review we present the current world status of DLT.

摘要

原位肝移植是治疗终末期肝病和某些严重代谢性疾病的一种既定方法。随着等待名单上的患者数量不断增加,以及可供使用的肝脏持续短缺,多米诺肝移植(DLT)成为进一步扩大器官捐献者库的一种选择。DLT 利用一名肝移植受者的已移植肝脏作为另一名患者的供体移植物。尽管这是一项具有挑战性的手术和后勤要求的手术,但在经验丰富的高容量移植中心可以取得极好的效果。在这篇综述中,我们介绍了 DLT 的当前世界现状。

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