College of Environment and Resources, Xiangtan University, Xiangtan 411105, China.
College of Resources and Environment, Hunan Agricultural University, Changsha 410128, China.
J Hazard Mater. 2020 Jul 15;394:122570. doi: 10.1016/j.jhazmat.2020.122570. Epub 2020 Mar 20.
The removal of antibiotics and resistance genes in wastewater treatment plants has attracted widespread attention, but the potential role of residual antibiotics in the disposal of waste activated sludge (WAS) has not been clearly understood. In this study, the effect of roxithromycin (ROX) on volatile fatty acid (VFA) recovery from WAS anaerobic fermentation was investigated. The experimental results showed that ROX made a positive contribution to the production of VFAs. With the increase of ROX dosages from 0 to 100 mg/kg TSS, the maximum accumulation of VFAs increased from 295 to 610 mg COD/L. Mechanism studies revealed that ROX promoted the solubilization of WAS by facilitating the disruption of extracellular polymeric substances. In addition, ROX enhanced the activity of acetate kinase and inhibited the activities of α-glucosidase and coenzyme F, and showed a stronger inhibitory effect on methane production than the hydrolysis process, thus resulting in an increase in VFA accumulation. These findings provide a new insight for the role of antibiotics in anaerobic fermentation of WAS.
污水处理厂中抗生素和抗性基因的去除已经引起了广泛关注，但残留抗生素在处理废活性污泥（WAS）中的潜在作用还没有被清楚地理解。在本研究中，研究了罗红霉素（ROX）对 WAS 厌氧发酵中挥发性脂肪酸（VFA）回收的影响。实验结果表明，ROX 对 VFA 的产生有积极贡献。随着 ROX 剂量从 0 增加到 100mg/kgTSS，VFA 的最大积累量从 295 增加到 610mgCOD/L。机理研究表明，ROX 通过促进细胞外聚合物的破坏来促进 WAS 的溶解。此外，ROX 增强了乙酸激酶的活性，抑制了α-葡萄糖苷酶和辅酶 F 的活性，并且对甲烷生成的抑制作用比水解过程更强，从而导致 VFA 积累增加。这些发现为抗生素在 WAS 厌氧发酵中的作用提供了新的见解。
