冠状动脉直径对冠状动脉内麦角新碱的双相反应。
Biphasic response of coronary arterial diameter to intracoronary ergonovine.
作者信息
Mohri M, Okamatsu S, Nakamura M
机构信息
Research Institute of Angiocardiology and Cardiovascular Clinic, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
出版信息
Clin Cardiol. 1988 Oct;11(10):710-4. doi: 10.1002/clc.4960111011.
This report presents a case of paradoxical coronary arterial dilation induced by intracoronary ergonovine. When compared with the control angiogram, the right coronary artery obviously dilated with selective, intracoronary administration of cumulative doses of 5 micrograms and 15 micrograms ergonovine without concomitant hemodynamic changes. Additional intracoronary infusion of 35 micrograms ergonovine into the right coronary artery inversely increased vascular tone of the vessel associated with a focal hyperconstriction. Such a biphasic response of arterial diameter to intracoronary ergonovine was also observed in the left coronary artery, but the degree of dilation was much smaller.
本报告介绍了一例由冠状动脉内注射麦角新碱引起的矛盾性冠状动脉扩张病例。与对照血管造影相比，在选择性冠状动脉内累积注射5微克和15微克麦角新碱时，右冠状动脉明显扩张，且未伴随血流动力学变化。向右冠状动脉额外注射35微克麦角新碱会使血管张力反向增加，并伴有局灶性血管收缩。在左冠状动脉也观察到动脉直径对冠状动脉内麦角新碱的这种双相反应，但扩张程度要小得多。
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