Shortt C, Madden A, Flynn A, Morrissey P A
Department of Nutrition, University College, Cork, Ireland.
Eur J Clin Nutr. 1988 Jul;42(7):595-603.
The relationship between dietary sodium intake (as assessed by the 24-h urinary excretion of sodium) and urinary calcium excretion was examined in a selected group of free-living Irish individuals (n = 94), under conditions in which the completeness of urine collections was assessed. Results indicated that there was a significant positive correlation between 24-h urinary sodium and calcium excretion for males (r = 0.56, P less than 0.001) and females (r = 0.35, P less than 0.01). In addition, linear regression analysis indicated that mean 24-h urinary calcium excretion increased by 39 mg and 26 mg for a 1 g increment in sodium intake for males and females, respectively. The relationship between dietary sodium intake and urinary calcium excretion was also examined in 12 healthy young adults under controlled dietary conditions. Urinary sodium and calcium excretion values over 24 h were positively correlated for males (r = 0.44, P less than 0.05) and females (r = 0.80, P less than 0.001). However, the relationship was only statistically significant for 5 of the 12 subjects when the data were analysed on an individual basis. Results of this study suggest that salt intake may be an important determinant of urinary calcium loss in certain individuals and, as such, may be a risk factor in the development of osteoporosis. However, further studies are required to establish whether low salt intakes have a beneficial effect on calcium balance in free-living individuals.
在一组选定的自由生活的爱尔兰人（n = 94）中，在评估尿液收集完整性的条件下，研究了饮食钠摄入量（通过24小时尿钠排泄量评估）与尿钙排泄之间的关系。结果表明，男性（r = 0.56，P < 0.001）和女性（r = 0.35，P < 0.01）的24小时尿钠和钙排泄之间存在显著正相关。此外，线性回归分析表明，男性和女性的钠摄入量每增加1克，24小时平均尿钙排泄量分别增加39毫克和26毫克。在12名健康年轻成年人的受控饮食条件下，也研究了饮食钠摄入量与尿钙排泄之间的关系。男性（r = 0.44，P < 0.05）和女性（r = 0.80，P < 0.001）的24小时尿钠和钙排泄值呈正相关。然而，当对个体数据进行分析时，12名受试者中只有5名的这种关系具有统计学意义。这项研究的结果表明，盐摄入量可能是某些个体尿钙流失的重要决定因素，因此可能是骨质疏松症发展的一个风险因素。然而，需要进一步研究来确定低盐摄入量是否对自由生活个体的钙平衡有有益影响。
