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在脊髓中通过实验诱导建立并鉴定脑内移植瘤系。

Establishment and characterization of an intracerebrally transplanted tumor line, induced experimentally in the spinal cord.

作者信息

Mennel H D

机构信息

Department of Neuropathology, Medical Center of Pathology, University of Marburg, FRG.

出版信息

Exp Pathol. 1988;33(3):165-72. doi: 10.1016/s0232-1513(88)80062-8.

Abstract

Transplanted tumor lines are useful to study open questions in human pathology and clinical research, particularly with the evaluation of therapeutic measures. Transplantation tumor lines derived from neoplasms in the nervous system originally induced with resorptive carcinogens are considered to be useful for these purposes. In this study observations on the histological pattern of original and intracerebrally transplanted new induced spinal cord tumors, mainly in early passages, has been investigated with the aim to improve the usefulness of the experimental model.

摘要

移植肿瘤系对于研究人类病理学和临床研究中的未解决问题很有用,特别是在评估治疗措施方面。源自最初由吸收性致癌物诱发的神经系统肿瘤的移植肿瘤系被认为适用于这些目的。在本研究中,主要针对早期传代的原始和脑内移植新诱导脊髓肿瘤的组织学模式进行了观察,目的是提高实验模型的实用性。

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