Loiseau P, Bories C, Gayral P, Wolf J G
Laboratoire de Parasitologie, Faculté de Pharmacie, Universite Paris-Sud, Chatenay-Malabry, France.
Farmaco Sci. 1988 Jul-Aug;43(7-8):657-63.
The trypanocidal activity of a new class of arsenical compounds, the spiroarsorans, was investigated against Trypanosoma brucei brucei. The most active compound was found to be effective at a dose of 30 mg.kg-1 and had low toxicity.
研究了一类新型砷化合物——螺砷化合物对布氏布氏锥虫的杀锥虫活性。发现最具活性的化合物在剂量为30毫克·千克⁻¹时有效,且毒性较低。