Allexcel, Inc., 1 Controls Drive, Shelton 06484, CT, United States.
Allexcel, Inc., 1 Controls Drive, Shelton 06484, CT, United States.
J Clin Neurosci. 2020 May;75:1-4. doi: 10.1016/j.jocn.2020.03.024. Epub 2020 Apr 1.
Parkinson's disease (PD) is a complex condition with a wide range of symptoms, like impaired movement, tremors, apathy and depression, and many other symptoms. The disease results from degeneration of dopaminergic neural cells. No cure at present but symptomatic some palliative treatments are available to slow down the disease progression. According to the Parkinson's Foundation every year in U.S., approximately 60,000 Americans diagnosed with PD. Nearly one million will be living with PD in the U.S. by 2020, which is more than the combined number of people diagnosed with multiple sclerosis, muscular dystrophy and Amyotrophic Lateral Sclerosis (ALS). There is no diagnostic test for PD, yet, but this article will review all kinds symptomatic and disease-modifying therapy.
帕金森病（PD）是一种复杂的疾病，具有广泛的症状，如运动障碍、震颤、冷漠和抑郁，以及许多其他症状。这种疾病是由多巴胺能神经元的退化引起的。目前尚无治愈方法，但有一些对症的姑息治疗可以减缓疾病的进展。根据帕金森基金会的数据，美国每年约有 6 万人被诊断出患有 PD。到 2020 年，将有近 100 万人患有 PD，这超过了多发性硬化症、肌肉萎缩症和肌萎缩性侧索硬化症（ALS）患者的总和。目前还没有针对 PD 的诊断测试，但本文将回顾各种对症和疾病修饰治疗。
