Li W W, Yew D T, Au C Y
Department of Anatomy, Chinese University of Hong Kong, Shatin.
Gegenbaurs Morphol Jahrb. 1988;134(4):529-39.
Albino mice were bled through the hearts and 1/3 ml of blood withdrawn from each animal. The choriocapillaries and the pigment epithelia of the eyes were selected for observations using the electron microscope. Morphological changes were apparent during the first 72 h after bleeding. Increase of vesicles in both the endothelial cells and the basal infoldings of pigment cells were features. Thickening of basal infoldings, thinning out of Bruch's membrane (with decrease content of fibrillary substances) as well as a transient disappearance of the diaphragms of pores of endothelial cells were also observed. Trypan blue dye was also found to have diffused into the retina in the first 24 h after bleeding. These processes appeared to augment the decreased nutrient supply to the retina after blood loss.
对白化小鼠进行心脏采血，每只动物采血量为1/3毫升。选取眼睛的脉络膜毛细血管和色素上皮用于电子显微镜观察。出血后最初72小时内出现明显的形态学变化。内皮细胞和色素细胞基底褶皱中的小泡增多是其特征。还观察到基底褶皱增厚、布鲁赫膜变薄（纤维状物质含量减少）以及内皮细胞孔隙隔膜短暂消失。在出血后的最初24小时内，还发现台盼蓝染料扩散到了视网膜中。这些过程似乎加剧了失血后视网膜营养供应的减少。
