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肥胖对脑卒中住院康复功能结局影响的系统评价。

A systematic review of the impact of obesity on stroke inpatient rehabilitation functional outcomes.

机构信息

Bridgepoint Active Healthcare, Sinai Health, Toronto, Canada.

Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada.

出版信息

NeuroRehabilitation. 2020;46(3):403-415. doi: 10.3233/NRE-192979.

Abstract

BACKGROUND

Obesity is a known risk factor for stroke, but its impact on functional recovery is less clear. Understanding the effect of obesity on functional recovery during inpatient rehabilitation will aid clinicians in patient counselling and help administrators with program planning.

OBJECTIVE

To determine if obesity affects the functional outcomes of adults undergoing inpatient stroke rehabilitation.

METHODS

MEDLINE, Embase, CINAHL, and Cochrane databases were searched using the subject headings and text word terms for stroke, rehabilitation, and obesity. Two independent reviewers screened the articles against pre-defined eligibility criteria and extracted the data. Outcomes of interest included FIM, mRS, Fugl-Meyer Assessment of Sensorimotor Recovery after Stroke, and Barthel Index.

RESULTS

Seven studies from five countries with a total of 3070 participants were included. There was significant heterogeneity among the studies in the BMI cut-off points and functional outcome measures used. Two studies found a positive association between obesity and functional outcome, two studies found no association, and three studies reported a negative relationship.

CONCLUSIONS

No conclusions could be drawn regarding whether the functional outcome of adults undergoing inpatient stroke rehabilitation differ between individuals with and without obesity.

摘要

背景

肥胖是中风的已知危险因素,但它对功能恢复的影响尚不清楚。了解肥胖对住院康复期间成年人功能恢复的影响将有助于临床医生为患者提供咨询,并帮助管理人员进行项目规划。

目的

确定肥胖是否影响接受住院脑卒中康复治疗的成年人的功能结局。

方法

使用脑卒中、康复和肥胖的主题词和文本词,在 MEDLINE、Embase、CINAHL 和 Cochrane 数据库中进行检索。两名独立的审查员根据预先确定的纳入标准筛选文章并提取数据。感兴趣的结局包括 FIM、mRS、脑卒中后感觉运动恢复的 Fugl-Meyer 评估和 Barthel 指数。

结果

从五个国家的七项研究中纳入了 3070 名参与者。研究之间在 BMI 切点和使用的功能结局测量方面存在显著异质性。两项研究发现肥胖与功能结局之间存在正相关,两项研究未发现相关性,三项研究报告存在负相关。

结论

对于接受住院脑卒中康复治疗的成年人,肥胖与非肥胖者的功能结局是否存在差异,无法得出结论。

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