Skjaerven R, Wilcox A J, Russell D
Section for Medical Informatics and Statistics, University of Bergen, Norway.
Int J Epidemiol. 1988 Dec;17(4):830-8. doi: 10.1093/ije/17.4.830.
A woman's successive offspring tend to have similar birthweights. We use data from the Medical Birth Registry of Norway to describe weight and perinatal mortality of second births given the weight of the mother's first birth. Mean weights among second births differ by as much as 1000 grams, depending on the weight of the first. Furthermore, the survival of the second baby at any given weight is strongly affected by its weight relative to the first baby's weight. A baby may be average size compared to the whole population, but small compared to its sibling; such a baby has the increased mortality that goes with being relatively small. For example, an infant of 3250 grams is relatively large if the mother's previous baby was 2250 grams, but relatively small if the previous birth weighed 4250 grams. In the first case, the mortality risk of the 3250-gram baby is 2.2 per thousand, while in the second case, risk for the same weight infant is 9.0, or four times higher. Implications of these observations for the more general analysis of birthweight and perinatal mortality are discussed.
女性连续生育的后代往往具有相似的出生体重。我们利用挪威医学出生登记处的数据,根据母亲首次生育的体重来描述第二次生育的体重及围产期死亡率。第二次生育的平均体重因首次生育的体重不同而相差多达1000克。此外,在任何给定体重下,第二个婴儿的存活情况受其相对于第一个婴儿体重的影响很大。一个婴儿与整个人口相比可能是平均体型,但与其兄弟姐妹相比则较小;这样的婴儿会因相对较小而有更高的死亡率。例如,如果母亲的前一个婴儿体重为2250克,那么一个体重3250克的婴儿相对较大,但如果前一次出生体重为4250克,那么这个婴儿就相对较小。在第一种情况下,体重3250克婴儿的死亡风险为千分之2.2,而在第二种情况下,相同体重婴儿的风险为9.0,即高出四倍。本文讨论了这些观察结果对出生体重和围产期死亡率更一般分析的影响。