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母羊对Fecundin(去甲雄三烯醇酮)免疫接种的生殖反应。

Reproductive response of ewes to immunization with Fecundin (ovandrotone).

作者信息

Meyer H H, Lewis R D

机构信息

Oregon State University, Corvallis 97331.

出版信息

J Anim Sci. 1988 Nov;66(11):2742-9. doi: 10.2527/jas1988.66112742x.

DOI:10.2527/jas1988.66112742x
PMID:3225236
Abstract

Ewes of five crossbred genotypes (total of 221 ewes) were immunized with a commercial preparation of androstenedione-7HSA in DEAE dextran adjuvant in a 2-yr trial. In yr 1 ewes were allocated within genotype to a 2 x 2 application of immunization and premating flushing. In yr 2 they were allocated within previous Fecundin treatment into either Fecundin-treated or control groups. First-time immunization with Fecundin increased ovulation rate by .70 ova/ewe in yr 1 and by .85 ova/ewe in yr 2 (P less than .05). Ewes treated in both years produced fewer ova than those treated in the 2nd yr only (P less than .05), but they did not differ in litter size. Although Fecundin reduced conception to first mating, the overall conception rate was not affected. Litter size of treated ewes was increased by .19 and .38 lambs/ewe lambing (P less than .05) in yr 1 and yr 2, respectively. Fecundin treatment in yr 1 produced a carry-over effect in yr 2 by increasing litter size by .26 lamb/ewe (P less than .05) while reducing conception to first mating. The litter size of ewes with two ovulations was reduced by Fecundin treatment in yr 1 (P less than .05) but showed no consistent pattern in yr 2. Overall, ewes with two ovulations produced .7 to .8 more lambs than ewes with one ovulation, and ewes with three ovulations produced .4 more lambs than those with two ovulations. Ewes of different genotypes did not differ in their response to Fecundin.

摘要

在一项为期两年的试验中,用含有二乙氨基乙基葡聚糖佐剂的雄烯二酮 - 7人血清白蛋白商业制剂对五种杂交基因型的母羊(共221只)进行免疫。在第一年,根据基因型将母羊分配到免疫和配种前冲洗的2×2处理组中。在第二年,根据之前的孕马血清促性腺激素处理情况将它们分配到孕马血清促性腺激素处理组或对照组。第一年首次使用孕马血清促性腺激素免疫使排卵率提高了0.70个卵子/母羊,第二年提高了0.85个卵子/母羊(P<0.05)。两年都接受处理的母羊排出的卵子比仅在第二年接受处理的母羊少(P<0.05),但它们的产羔数没有差异。虽然孕马血清促性腺激素降低了首次配种的受孕率,但总体受孕率不受影响。处理过的母羊的产羔数在第一年和第二年分别增加了0.19只和0.38只羔羊/产羔母羊(P<0.05)。第一年的孕马血清促性腺激素处理在第二年产生了延续效应,产羔数增加了0.26只羔羊/母羊(P<0.05),同时降低了首次配种的受孕率。孕马血清促性腺激素处理使第一年有两次排卵的母羊的产羔数减少(P<0.05),但在第二年没有一致的规律。总体而言,有两次排卵的母羊比有一次排卵的母羊多产0.7至0.8只羔羊,有三次排卵的母羊比有两次排卵的母羊多产0.4只羔羊。不同基因型的母羊对孕马血清促性腺激素的反应没有差异。

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