Fraioli J P, Schwarzenberg L
Hôpital Paul Brousse, Villejuif.
J Chir (Paris). 1988 Nov;125(11):638-41.
From june 1983 to december 1987, 441 direct accesses were implanted, 237 intravenous, 51 intraperitoneal and 153 intra-arterial. The surgical procedure, the indications, the post-operatory and later complications and the issue of the direct intravenous accesses implanted by the same surgical team are presented. 237 direct access implants were placed intravenously in 228 patients. There are many indications for implanting direct access: absence of a superficial venous network, continuous chemotherapy, preservation of the superficial venous network, thrombosis of the hepatic artery after, inoperable hepatic metastasis (jaundice). Direct venous access was implanted for many pathologies essentially for breast cancer (120 cases), large bowel cancer (36 cases). Surgical procedure for direct intravenous access is easy with catheter's control with fluoroscopy monitoring. Only rarely did any later complication occur when using the direct intravenous access (12 cases) representing 5% of all complications. Certain precautions should be taken to reduce the number of complications. Prophylactic antibiotic therapy, surgical procedure for implanting the direct access excision of excess fatty subcutaneous tissue, minutious skin disinfection, heparinization, avoid using the chamber for blood sampling, use intra-arterial direct access. Direct access is used either for sequential chemotherapy or for continuous protocols which vary in length.
1983年6月至1987年12月期间,共植入441个直接通路,其中237个为静脉内通路,51个为腹腔内通路,153个为动脉内通路。本文介绍了手术操作、适应证、术后及后期并发症,以及同一手术团队植入的直接静脉通路的相关问题。228例患者共植入237个直接静脉通路。植入直接通路有多种适应证:无浅表静脉网络、持续化疗、保留浅表静脉网络、肝动脉血栓形成后、无法手术的肝转移(黄疸)。直接静脉通路主要用于多种疾病,尤其是乳腺癌(120例)、大肠癌(36例)。在荧光透视监测下控制导管,直接静脉通路的手术操作很容易。使用直接静脉通路时,后期并发症很少发生(12例),占所有并发症的5%。应采取某些预防措施以减少并发症的数量。预防性抗生素治疗、植入直接通路时切除多余的皮下脂肪组织的手术操作、细致的皮肤消毒、肝素化、避免使用腔室进行采血、使用动脉内直接通路。直接通路可用于序贯化疗或不同时长的持续方案。