Redondo González Olga, Olteanu Olteanu Filip Camil, Arechederra Calderón Juan José, Bravo Villaseñor Clara María, Miras Aguilar Isabel, Rodríguez Arbaizar Jorge
Servicio de Medicina Preventiva, Hospital Universitario de Guadalajara, Guadalajara, España.
Servicio de Pediatría, Hospital Universitario de Guadalajara, Guadalajara, España.
Med Clin (Barc). 2020 Aug 14;155(3):119-122. doi: 10.1016/j.medcli.2020.01.021. Epub 2020 Apr 3.
The objective was to estimate the effectiveness of inactivated trivalent vaccine (VE) in preventing hospital flu care (HFC) in Guadalajara, Castile-La Mancha (CLM), Spain, 2018-19 season.
Retrospective cohort study (40/2018 to 13/2019 weeks).
Microbiology programme; electronic medical history; population census (INE, 1/7/2018).
Population requiring HFC (hospital emergencies and/or emergency observation unit and/or hospital admissions), confirmed by antigenic test and/or PCR. Preventive fractions [PFv(vaccinated) and PFp(population)] and Necessary number of patients to be vaccinated (NNV) were calculated.
228 HFT occurred [cumulative incidence rate (IR)=8.9/10; ≥65 years=65%; vaccination coverage=13% (≥65 years=58%); mortality=9%); maximum incidence in the 6th week (IR=1.7/10) (in CLM, in 4th)]. Highest peak of RSV occurred in the 3rd (in CLM, in the 52th). PFv (14-65 years) was 96% (PFp=58%) and in ≥65, 32% (PFp=21%). NNV=414. As in Spain, influenza virus A predominated, with A(H3N2) being 13% more prevalent (strain not included in the vaccine).
The season was delayed by sustained VRS circulation. The VE was lower than the national one. It is be essential to promote future campaigns to improve vaccination coverage.
