Zhu Mengliang, Xing Peipei, Zhou Yabin, Gong Lei, Zhang Jinghui, Qi Dongdong, Bian Yongzhong, Du Hongwu, Jiang Jianzhuang
Beijing Key Laboratory for Science and Application of Functional Molecular and Crystalline Materials, Department of Chemistry, University of Science and Technology Beijing, Beijing 100083, China.
J Mater Chem B. 2018 Jul 21;6(27):4422-4426. doi: 10.1039/c8tb00883c. Epub 2018 Jun 28.
BODIPY-based probes were developed for the ratiometric fluorescence detection of pH values. They showed high sensitivity under acidic conditions via a protonation-modulated ICT mechanism and could selectively stain lysosomes, and thus could be applied for imaging and detecting abnormal pH decreases in live cells.