• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

放疗后成功重返飞行岗位的鼻咽癌战斗机飞行员:病例系列。

Fighter Pilots With Nasopharyngeal Carcinoma Successfully Returning to Flight After Radiotherapy: A Case Series.

机构信息

Department of Otorhinolaryngology, Tri-Serive General Hospital-SongShan Branch, National Defense Medical Center, Taipei, Taiwan. No. 325, Chengong Rd., Sec. 2, Neihu, Taipei 114, Taiwan.

Graduate Institute of Injury Prevention and Control, Taipei Medical University, Taipei, Taiwan. No. 250, Wuxing St., Xinyi dist., Taipei 110, Taiwan.

出版信息

Mil Med. 2020 Mar 2;185(3-4):e522-e525. doi: 10.1093/milmed/usz276.

DOI:10.1093/milmed/usz276
PMID:32255190
Abstract

For nasopharyngeal carcinoma (NPC), radiotherapy is the primary treatment. However, complications occur after radiation to the nasopharynx, which could potentially affect the flying safety. Four fighter pilots with NPC were reported. With early to locally advanced NPC, they received radiotherapy with or without concurrent chemotherapy. The prescribed radiation dose was 70 Gy to the primary tumor over the nasopharynx. Before treatment, all patients presented with various degrees of hearing loss on pure tone audiometry (main frequencies of 20-45 dB at 3-4.5 kHz for affected ears). After the full course of radiotherapy, tumor regression was noticed during months to years of follow-ups. The follow-up audiometry evaluation showed gradually recovered hearing function (average improvement of 5 dB at pretreatment frequencies) in all pilots. They then returned back to the flight line on annual waiver points. Here, we conclude that fighter pilots with NPC could successfully return to the flight line after radiotherapy. However, detailed physical examinations and confirmation of adaptation to flying condition are warranted.

摘要

对于鼻咽癌(NPC),放射治疗是主要治疗方法。然而,鼻咽部放射后会出现并发症,这可能会影响飞行安全。报告了 4 名患有 NPC 的战斗机飞行员。对于早期到局部晚期 NPC,他们接受了放疗联合或不联合化疗。鼻咽原发肿瘤的规定放射剂量为 70Gy。治疗前,所有患者的纯音听阈检查(受影响耳的 3-4.5kHz 主要频率为 20-45dB)均显示出不同程度的听力损失。放射治疗后,经过数月至数年的随访,肿瘤出现了消退。随访听力学评估显示,所有飞行员的听力功能逐渐恢复(治疗前频率的平均改善 5dB)。然后,他们凭年度豁免积分回到飞行岗位。在这里,我们得出结论,接受放射治疗的 NPC 战斗机飞行员可以成功返回飞行岗位。然而,需要进行详细的体检并确认适应飞行条件。

相似文献

1
Fighter Pilots With Nasopharyngeal Carcinoma Successfully Returning to Flight After Radiotherapy: A Case Series.放疗后成功重返飞行岗位的鼻咽癌战斗机飞行员:病例系列。
Mil Med. 2020 Mar 2;185(3-4):e522-e525. doi: 10.1093/milmed/usz276.
2
Radiotherapeutic treatment of a fighter pilot with nasopharyngeal carcinoma.
Aviat Space Environ Med. 2014 Oct;85(10):1056-60. doi: 10.3357/ASEM.3901.2014.
3
Dosimetric parameters associated with conductive or sensorineural hearing loss 5 years after intensity-modulated radiation therapy in nasopharyngeal carcinoma.鼻咽癌调强放射治疗5年后与传导性或感音神经性听力损失相关的剂量学参数。
Acta Otolaryngol. 2019 Mar;139(3):263-268. doi: 10.1080/00016489.2019.1566778. Epub 2019 Mar 14.
4
Sensorineural Hearing Loss in Nasopharyngeal Carcinoma Survivors in the Modern Treatment Era - The Early and Late Effects of Radiation and Cisplatin.现代治疗时代鼻咽癌幸存者的感音神经性听力损失——放疗和顺铂的早期及晚期影响
Clin Oncol (R Coll Radiol). 2022 Apr;34(4):e160-e167. doi: 10.1016/j.clon.2021.10.013. Epub 2021 Nov 10.
5
Long-term hearing status after radiotherapy for nasopharyngeal carcinoma.鼻咽癌放疗后的长期听力状况。
Auris Nasus Larynx. 1998 Jan;25(1):21-4. doi: 10.1016/s0385-8146(97)10009-8.
6
[Clinical analyses of sudden sensorineural hearing loss in 14 nasopharyngeal carcinomas following radiotherapy].[14例鼻咽癌放疗后突发感音神经性听力损失的临床分析]
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2011 Sep;46(9):705-8.
7
Hearing in military pilots: one-time audiometry in pilots of fighters, transports, and helicopters.军事飞行员的听力:战斗机、运输机和直升机飞行员的一次性听力测定
Aviat Space Environ Med. 2006 Jan;77(1):57-61.
8
A long-term study on hearing status in patients with nasopharyngeal carcinoma after radiotherapy.鼻咽癌患者放疗后听力状况的长期研究。
Otol Neurotol. 2004 Mar;25(2):168-73. doi: 10.1097/00129492-200403000-00015.
9
Long-term sensorineural hearing deficit following radiotherapy in patients suffering from nasopharyngeal carcinoma: A prospective study.鼻咽癌患者放疗后长期感音神经性听力缺损:一项前瞻性研究。
Head Neck. 1999 Sep;21(6):547-53. doi: 10.1002/(sici)1097-0347(199909)21:6<547::aid-hed8>3.0.co;2-y.
10
Methylprednisolone use during radiotherapy extenuates hearing loss in patients with nasopharyngeal carcinoma.鼻咽癌患者放疗期间使用甲泼尼龙可减轻听力损失。
Laryngoscope. 2016 Jan;126(1):100-3. doi: 10.1002/lary.25527. Epub 2015 Aug 26.