Clin Lab. 2020 Apr 1;66(4). doi: 10.7754/Clin.Lab.2019.190726.
Hematology analysis is a common test among patients in hospital. However, manual verification of hematology analysis is time consuming and tedious, with variation between inter-individual laboratory workers. This study was to establish and validate a set of autoverification rules for hematology analysis in the department of laboratory medicine, Zhongshan Hospital of Sun Yatsen University.
Hematology analysis was measured by a Sysmex XN-9000 hematology system in the Department of Laboratory Medicine, Zhongshan Hospital of Sun Yatsen University. SYSMEX Laboman EasyAccess 6.0 and the laboratory information system were used to construct the algorithm and design the autoverification rules of hematology analysis according to Clinical and Laboratory Standards Institute document Auto 10A and 41 rules of Hematology Review Criteria. The laboratory turnaround time (TAT), autoverification pass rates, false positive, false negative, and the average error rate were verified after implementing autoverification rules.
Approximate 1,300 specimens were collected daily and transferred to our laboratory for hematology analysis; that is necessary to build a database and to design autoverification rules. The average autoverification passing rate was 81%; the false positive rate was 13.6%; the false negative rate and the average error rate was nearly zero, indicating that incorrect reports were almost eliminated. Moreover, since implementing autoverification, the TAT was reduced by 27.0% in in-patient reports, by 21.9% in out-patient reports, and by 39.0% in emergency reports, which enhanced the productivity in our laboratory.
Our laboratory accelerated verification and decreased TAT and the odds of human review errors in the released results since implementing the autoverification. Thus, we can save more time and concentrate on verifying the abnormal results and processing emergency tests.
血液分析是医院患者的常见检查。然而，血液分析的人工验证既耗时又乏味，且个体实验室工作人员之间存在差异。本研究旨在为中山大学孙逸仙纪念医院检验科建立并验证一套血液分析自动验证规则。
血液分析由中山大学孙逸仙纪念医院检验科的 Sysmex XN-9000 血液系统进行测量。使用 SYSMEX Laboman EasyAccess 6.0 和实验室信息系统，根据临床和实验室标准协会文件 Auto 10A 和血液学审核标准的 41 条规则，构建算法并设计血液分析自动验证规则。实施自动验证规则后，验证实验室周转时间（TAT）、自动验证通过率、假阳性、假阴性和平均误差率。
每天大约有 1300 个标本被收集并转移到我们的实验室进行血液分析；这有必要建立一个数据库并设计自动验证规则。平均自动验证通过率为 81%；假阳性率为 13.6%；假阴性率和平均误差率几乎为零，表明几乎消除了错误报告。此外，自从实施自动验证以来，住院报告的 TAT 降低了 27.0%，门诊报告降低了 21.9%，急诊报告降低了 39.0%，提高了实验室的生产力。
自从实施自动验证以来，我们实验室加快了验证速度，减少了 TAT 和发布结果中人为审核错误的几率。因此，我们可以节省更多的时间，专注于验证异常结果和处理紧急测试。
