Urology Department, Instituto Português de Oncologia Francisco Gentil, Coimbra.
Arch Ital Urol Androl. 2020 Apr 6;92(1):45-49. doi: 10.4081/aiua.2020.1.45.
Patients with localized prostate cancer (PCa) are active participants in the choice of treatment.
To access the effects of social and demographic factors in the choice of treatment in cases of localized PCa, in a Portuguese population.
Identification of all patients with the diagnosis of localized PCa in the last four years in an oncological centre. Evaluation of the effects of sociodemographic factors (age, profession, literacy, marital status, district and number of inhabitants of the place of residence) in the choice of treatment.
300 patients with localized PCa were evaluated: 17.3% (n = 52) opted for radical prostatectomy (RP); 39,3% had (n = 118) external radiotherapy; brachytherapy in 29.3% (n = 88) and other options (active surveillance, cryotherapy and hormonal therapy) in 14.1% (n = 42). In relation to surgical treatment (RP) the following results were obtained: a) > 70 years: 3.9% (n = 5); ≤ 70 years: 27.5% (n = 47), p < 0.001; b) primary sector: 10.3% (n = 3); secondary sector: 16.2% (n = 27); tertiary sector: 24.1% (n = 21); quaternary sector: 8.3% (n = 1), p = 0.296; c) marital status married: 17.9% (n = 47); single: 0% (n = 0); divorced: 25.0% (n = 5); widow: 0% (n = 0), p = 0.734; d) residency in a city: 14.1% (n = 13); city > 4000 habitants: 22.7% (n = 15); city ≤ 4000 habitants: 16.9% (n = 24), p = 0.701. Using multinomial regression with age (p = 0.001), district (p = 0.035), marital status (p = 0.027) and profession (0.179), this model explained 17.2%-28.4% of therapeutic choices (p < 0.001).
The main socioeconomical factor that influence treatment choice was age. Unmarried patients over 70 years choose less radical prostatectomy. Other sociodemographic factors have minor influence in the choice of the treatment.
患有局限性前列腺癌（PCa）的患者是治疗选择的积极参与者。
评估葡萄牙人群中社会人口因素对局限性 PCa 治疗选择的影响。
在肿瘤中心确定过去四年中所有诊断为局限性 PCa 的患者。评估社会人口因素（年龄、职业、文化程度、婚姻状况、地区和居住地居民人数）对治疗选择的影响。
共评估了 300 例局限性 PCa 患者：17.3%（n = 52）选择根治性前列腺切除术（RP）；39.3%接受（n = 118）外照射放疗；29.3%接受近距离放射治疗（n = 88），14.1%接受其他选择（主动监测、冷冻治疗和激素治疗）（n = 42）。关于手术治疗（RP），得到以下结果：a）> 70 岁：3.9%（n = 5）；≤ 70 岁：27.5%（n = 47），p < 0.001；b）初级部门：10.3%（n = 3）；二级部门：16.2%（n = 27）；三级部门：24.1%（n = 21）；四级部门：8.3%（n = 1），p = 0.296；c）婚姻状况已婚：17.9%（n = 47）；单身：0%（n = 0）；离婚：25.0%（n = 5）；丧偶：0%（n = 0），p = 0.734；d）居住在城市：14.1%（n = 13）；城市> 4000 居民：22.7%（n = 15）；城市≤ 4000 居民：16.9%（n = 24），p = 0.701。使用包含年龄（p = 0.001）、地区（p = 0.035）、婚姻状况（p = 0.027）和职业（0.179）的多项回归模型，该模型解释了 17.2%-28.4%的治疗选择（p < 0.001）。
影响治疗选择的主要社会经济因素是年龄。70 岁以上未婚患者选择根治性前列腺切除术的可能性较小。其他社会人口因素对治疗选择的影响较小。
