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比较半刚性输尿管镜、软性输尿管镜和冲击波碎石术治疗 11-20mm 近端输尿管结石的初始治疗效果。

Comparison of semirigid ureteroscopy, flexible ureteroscopy, and shock wave lithotripsy for initial treatment of 11-20 mm proximal ureteral stones.

机构信息

Department of Urology, Dıskapı Yıldırım Beyazıt Training and Research Hospital, Health Sciences University, Ankara.

出版信息

Arch Ital Urol Androl. 2020 Apr 6;92(1):39-44. doi: 10.4081/aiua.2020.1.39.

Abstract

OBJECTIVE

We aimed to retrospectively evaluate the effectiveness and safety of flexible ureteroscopy (f-URS), semirigid ureteroscopy (sr-URS), and shock wave lithotripsy (SWL) to treat single 11-20 mm stones in the proximal ureter.

MATERIALS AND METHODS

Patients treated at our clinic for 11-20 mm single stones in the proximal ureter who underwent f-URS, sr-URS or SWL as initial lithotripsy methods were compared in terms of their clinical characteristics and treatment outcomes.

RESULTS

A comparison among 201 patients who had undergone f-URS, 119 patients who had undergone sr-URS, and 162 patients who had undergone SWL showed no significant baseline differences in patients' demographic and stone characteristics. Stone-free rates on the 15th day and 3rd month were higher with f-URS (89.6% and 97%, respectively) than with sr-URS (67.2% and 94.1%, respectively) and SWL (41.4% and 79.0%, respectively; all p < 0.001). Retreatment rates were significantly higher with SWL than with the other two modalities (p < 0.001); auxiliary procedure rates were significantly lower with f-URS than with the other two modalities (p < 0.001). Treatment-related complication rate at the end of the 3rd month was lower with f-URS than with SWL (p = 0.022). Furthermore, f-URS was more effective than sr-URS for treating impacted stones.

CONCLUSIONS

We found that f-URS was highly successful as an initial lithotripsy procedure for medium-sized proximal ureteral stones, and it helped achieve early stone-free outcomes with a lower need for retreatment and auxiliary procedures, lower complication rates, and higher effectiveness on the impacted stones compared with sr-URS and SWL.

摘要

目的

本研究旨在回顾性评估软性输尿管镜(f-URS)、半硬性输尿管镜(sr-URS)和体外冲击波碎石术(SWL)治疗近端输尿管单发 11-20mm 结石的有效性和安全性。

材料和方法

本研究比较了在我院接受治疗的 11-20mm 单发近端输尿管结石患者,比较了行 f-URS、sr-URS 或 SWL 作为初始碎石方法的患者的临床特征和治疗结局。

结果

201 例行 f-URS、119 例行 sr-URS 和 162 例行 SWL 的患者的比较显示,患者的人口统计学和结石特征无明显基线差异。f-URS 的第 15 天和第 3 个月的无石率(分别为 89.6%和 97%)高于 sr-URS(分别为 67.2%和 94.1%)和 SWL(分别为 41.4%和 79.0%;均 P<0.001)。SWL 的再治疗率明显高于其他两种方法(P<0.001);f-URS 的辅助手术率明显低于其他两种方法(P<0.001)。f-URS 的 3 个月时治疗相关并发症率低于 SWL(P=0.022)。此外,f-URS 治疗嵌顿性结石的效果优于 sr-URS。

结论

我们发现,f-URS 作为治疗中等大小近端输尿管结石的初始碎石方法非常有效,与 sr-URS 和 SWL 相比,它有助于更早地实现无石结局,降低再治疗和辅助手术的需求,降低并发症发生率,对嵌顿性结石的疗效更高。

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