Urology Unit, Second University of Naples, Naples, Italy.
Department of Urology, SLK-Kliniken Heilbronn, Heilbronn, Germany.
Urolithiasis. 2017 Dec;45(6):563-572. doi: 10.1007/s00240-017-0960-7. Epub 2017 Feb 23.
To analyze the current evidence on the use of ureteroscopy (URS) and extracorporeal shock wave lithotripsy (ESWL) for the management of obstructing ureteral stones in emergent setting.
A systematic literature review was performed up to June 2016 using Pubmed and Ovid databases to identify pertinent studies. The PRISMA criteria were followed for article selection. Separate searches were done using a combinations of several search terms: "laser lithotripsy", "ureteroscopy", "extracorporeal shock wave lithotripsy", "ESWL", "rapid", "immediate", "early", "delayed", "late", "ureteral stones", "kidney stones", "renal stones". Only titles related to emergent/rapid/immediate/early (as viably defined in each study) versus delayed/late treatment of ureteral stones with either URS and/or ESWL were considered for screening. Demographics and operative outcomes were compared between emergent and delayed lithotripsy. RevMan review manager software was used to perform data analysis.
Four studies comparing emergent (n = 526) versus delayed (n = 987) URS and six studies comparing emergent (n = 356) versus delayed (n = 355) SWL were included in the analysis. Emergent URS did not show any significant difference in terms of stone-free rate (91.2 versus 90.9%; OR 1.04; CI 0.71, 1.52; p = 0.84), complication rate (8.7% for emergent versus 11.5% for delayed; OR 0.94; CI 0.65, 1.36; p = 0.74) and need for auxiliary procedures (OR 0.85; CI 0.42, 1.7; p = 0.85) when compared to delayed URS. Emergent ESWL was associated with a higher likelihood of stone free status (OR 2.2; CI 1.55, 3.17; p < 0.001) and a lower likelihood of need for auxiliary maneuvers (OR 0.49; CI 0.33, 0.72; p < 0.001) than the delayed procedure. No differences in complication rates were noticed between the emergent and delayed ESWL (p = 0.37).
Emergent lithotripsy, either ureteroscopic or extracorporeal, can be offered as an effective and safe treatment for patients with symptomatic ureteral stone. If amenable to ESWL, based on stone and patient characteristics, an emergent approach should be strongly considered. Ureteroscopy in the emergent setting is mostly reserved for distally located stones. The implementation of these therapeutic approaches is likely to be dictated by their availability.
分析在紧急情况下使用输尿管镜检查术(URS)和体外冲击波碎石术(ESWL)治疗输尿管梗阻性结石的现有证据。
使用 Pubmed 和 Ovid 数据库对截至 2016 年 6 月的相关文献进行系统评价,以确定相关研究。遵循 PRISMA 标准进行文章选择。使用多种搜索词的组合分别进行单独搜索:“激光碎石术”、“输尿管镜检查术”、“体外冲击波碎石术”、“ESWL”、“快速”、“即刻”、“早期”、“延迟”、“晚期”、“输尿管结石”、“肾结石”、“肾石”。仅考虑与紧急/即刻/早期(如每项研究中明确定义)与 URS 和/或 ESWL 治疗输尿管结石的延迟/晚期治疗相关的标题进行筛选。对紧急和延迟碎石术的患者人口统计学和手术结果进行比较。RevMan 评论经理软件用于数据分析。
纳入了 4 项比较紧急(n=526)与延迟(n=987)URS 和 6 项比较紧急(n=356)与延迟(n=355)SWL 的研究。与延迟 URS 相比,紧急 URS 并未显示出在无结石率(91.2%比 90.9%;OR 1.04;CI 0.71, 1.52;p=0.84)、并发症发生率(紧急 8.7%,延迟 11.5%;OR 0.94;CI 0.65, 1.36;p=0.74)和辅助程序需要(OR 0.85;CI 0.42, 1.7;p=0.85)方面有任何显著差异。与延迟 ESWL 相比,紧急 ESWL 更有可能达到无结石状态(OR 2.2;CI 1.55, 3.17;p<0.001),且更不可能需要辅助操作(OR 0.49;CI 0.33, 0.72;p<0.001)。紧急和延迟 ESWL 的并发症发生率无差异(p=0.37)。
对于有症状的输尿管结石患者,紧急输尿管镜检查或体外冲击波碎石术都可以作为一种有效且安全的治疗方法。如果适合 ESWL,根据结石和患者特征,应强烈考虑紧急方法。在紧急情况下进行输尿管镜检查主要适用于位于远端的结石。这些治疗方法的实施可能取决于它们的可用性。