Boysen M, Scott H, Hovig T, Wetteland J, Kolbenstvedt A
Department of Otolaryngology, National Hospital of Norway, Rikshospitalet, Norway.
J Laryngol Otol. 1988 Dec;102(12):1185-8. doi: 10.1017/s0022215100107674.
Adult rhabdomyoma is a benign neoplasm of skeletal muscle origin, which mainly occurs in the head and neck region. Because of its rarity the diagnosis may be missed, especially if cross-striations cannot be demonstrated by light microscopy. By applying supplementary diagnostic evaluation with immunohistochemistry and electron microscopy, the diagnosis is established. Positive staining with desmin unequivocally demonstrates that the tumour cells are derived from muscle tissue. The presence of myofibrils, Z-bands and numerous mitochondria by ultrastructural examination are characteristic features of this tumour.
成人横纹肌瘤是一种起源于骨骼肌的良性肿瘤，主要发生在头颈部区域。由于其罕见性，可能会漏诊，尤其是在光镜下无法显示横纹时。通过应用免疫组织化学和电子显微镜等辅助诊断评估方法，可以确立诊断。结蛋白阳性染色明确表明肿瘤细胞来源于肌肉组织。超微结构检查发现肌原纤维、Z带和大量线粒体的存在是该肿瘤的特征性表现。
