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白癜风患者的听力异常:一项基于医院的横断面研究。

Audiological Abnormalities in Vitiligo Patients: A Hospital-Based Cross-Sectional Study.

作者信息

Prabha Neel, Arora Ripudaman, Chhabra Namrata, Jati Monalisa, Nagarkar Nitin M

机构信息

Department of Dermatology, Venereology and Leprology, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.

Department of ENT & HNS, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.

出版信息

Int Arch Otorhinolaryngol. 2020 Apr;24(2):e149-e153. doi: 10.1055/s-0039-1696700. Epub 2019 Nov 4.

Abstract

There are some discrepancies in the literature about the influence of vitiligo on auditory functions. According to some authors, vitiligo influences hearing, whereas others question such influence. Therefore, we conducted a study to evaluate audiological functions in vitiligo patients.  To determine the effect of vitiligo on auditory functions.  A hospital-based observational study was done from January 2017 to July 2017. Clinically diagnosed cases of vitiligo were enrolled for the study. A complete otological examination was conducted in all patients.  Fifty-two patients (male: female 28:24) were included in the study. Ten patients (19.2%) had sensorineural hearing loss (SNHL). Seven patients (13.5%) had bilateral and 3 (5.7%) had unilateral SNHL. High frequency loss was seen in 17 out of 20 ears (10 affected patients), 6 ears had both low and high-frequency hearing loss. Of 12 ears with speech frequency involvement, mild hearing loss was seen in 5 and moderate to severe in 1 ear. Most cases of SNHL were detected in the age group 41 to 60 years old (63.6%), which was statistically significant ( -value 0.00).  The results of this study suggest that vitiligo patients require routine monitoring for auditory functions for early identification of SNHL. Older subjects with vitiligo might be at a higher risk for audiological abnormalities. These patients should also be informed regarding the associated risk with noise and ototoxic drug exposure.

摘要

关于白癜风对听觉功能的影响,文献中存在一些差异。一些作者认为,白癜风会影响听力,而另一些人则对这种影响提出质疑。因此,我们进行了一项研究,以评估白癜风患者的听力学功能。

为了确定白癜风对听觉功能的影响。

2017年1月至2017年7月进行了一项基于医院的观察性研究。临床诊断为白癜风的病例被纳入研究。对所有患者进行了全面的耳科检查。

52例患者(男∶女为28∶24)被纳入研究。10例患者(19.2%)患有感音神经性听力损失(SNHL)。7例患者(13.5%)为双侧SNHL,3例患者(5.7%)为单侧SNHL。20只耳朵中有17只(10例受累患者)出现高频听力损失,6只耳朵同时存在低频和高频听力损失。在12只出现言语频率受累的耳朵中,5只耳朵有轻度听力损失,1只耳朵有中度至重度听力损失。大多数SNHL病例在41至60岁年龄组中被检测到(63.6%),具有统计学意义(P值0.00)。

本研究结果表明,白癜风患者需要对听觉功能进行常规监测,以便早期发现SNHL。老年白癜风患者可能发生听力学异常的风险更高。还应告知这些患者噪声和耳毒性药物暴露的相关风险。

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Audiological abnormalities in patients with vitiligo.白癜风患者的听力异常。
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Association between vitiligo and hearing loss.白癜风与听力损失之间的关联。
J Am Acad Dermatol. 2021 Dec;85(6):1465-1472. doi: 10.1016/j.jaad.2020.12.029. Epub 2021 Jan 22.
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本文引用的文献

1
Assessment of auditory and vestibular functions in vitiligo patients.白癜风患者听觉和前庭功能评估。
J Otol. 2017 Sep;12(3):143-149. doi: 10.1016/j.joto.2017.07.001. Epub 2017 Jul 18.
8
Audiological and transient evoked otoacoustic emission findings in patients with vitiligo.白癜风患者的听力学和瞬态诱发耳声发射结果。
Otolaryngol Head Neck Surg. 2010 Mar;142(3):409-14. doi: 10.1016/j.otohns.2009.11.007. Epub 2010 Jan 22.
10
Clinical analysis of hearing levels in vitiligo patients.白癜风患者听力水平的临床分析
Eur J Dermatol. 2009 Jan-Feb;19(1):50-6. doi: 10.1684/ejd.2008.0563. Epub 2008 Dec 5.

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