Agashe Mandar, Vaidya Sandeep, Dhamele Jaideep, Chauhan Hitesh, Naik Premal, Nagda Taral
Agashe's Paediatric SuperSpeciality Care, Dr. Agashe's Hospital, Off LBS Road, Near Kalpana Talkies, Kurla (W), Mumbai, 400070 India.
Indian J Orthop. 2020 Feb 11;54(2):194-199. doi: 10.1007/s43465-019-00029-x. eCollection 2020 Apr.
CT-guided percutaneous drill resection (PDR) for osteoid osteoma fell out of vogue with the advent of radiofrequency ablation (RFA). However, the routine use of RFA is offset by its high cost and need for specialized instrumentation.
This study is an analysis of our series of patients treated with PDR, to know its efficacy, safety and cost-effectiveness.
This study is a retrospective analysis of prospectively collected data of 33 patients with a mean age of 10.03 years (2-21 years 13:10 M:F). The proximal femur was the commonest location, followed by shaft femur, tibial shaft, pubic ramus and lateral humeral condyle. Three were recurrences. The procedures were performed by one of four fellowship-trained paediatric orthopaedic surgeons, using a standard protocol with the help of a radiologist. CT-guided drilling was performed under sedation/short general anaesthesia using a guidewire for identification, followed by sequential drilling using a 6.5 mm cannulated drill or a triple ream drill. Patients were hospitalized overnight for pain relief and allowed protected weight bearing as per pain tolerance. They were evaluated weekly for 2 weeks and 3 monthly thereafter.
The mean final follow-up was 19.72 months (6 months to 58 months). All patients had complete resolution of symptoms within 3 days of the procedure. There were no major complications and there were two minor complications (haematoma and cutaneous hypoaesthesia). There were no recurrences till the last follow-up.
This study, one of the first and largest from India about CT-guided PDR, shows that this method can still be safely and effectively used as a primary treatment modality in OO, especially in economically challenged population. It is much more cost-effective than RFA, can be used even for recurrent tumours and can be safely be performed by a general orthopaedic surgeon without any special instrumentation.
随着射频消融(RFA)的出现,CT引导下经皮钻孔切除术(PDR)治疗骨样骨瘤已不再流行。然而,RFA的常规使用因成本高和需要专门的仪器而受到影响。
本研究分析了我们采用PDR治疗的一系列患者,以了解其疗效、安全性和成本效益。
本研究是对前瞻性收集的33例患者数据的回顾性分析,患者平均年龄为10.03岁(2至21岁,男13例:女10例)。股骨近端是最常见的部位,其次是股骨干、胫骨干、耻骨支和肱骨外侧髁。有3例复发。手术由4名接受过专科培训的小儿骨科医生之一进行,在放射科医生的帮助下采用标准方案。在镇静/短效全身麻醉下,使用导丝进行CT引导下钻孔以进行定位,随后使用6.5毫米空心钻或三刃扩孔钻依次钻孔。患者住院过夜以缓解疼痛,并根据疼痛耐受情况允许保护性负重。术后每周评估2周,之后每3个月评估一次。
平均最终随访时间为19.72个月(6个月至58个月)。所有患者在术后3天内症状均完全缓解。无重大并发症,有2例轻微并发症(血肿和皮肤感觉减退)。直至最后一次随访均无复发。
本研究是印度关于CT引导下PDR的首批且规模最大的研究之一,表明该方法仍可作为骨样骨瘤的一种安全有效的主要治疗方式,尤其适用于经济条件较差的人群。它比RFA更具成本效益,甚至可用于复发性肿瘤,普通骨科医生无需任何特殊仪器即可安全实施。