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直面显微镜下多血管炎(GPA):导致诊断延误的错失良机。

Look granulomatosis with polyangiitis (GPA) straight in the face: missed opportunities leading to a delayed diagnosis.

作者信息

Rolle N, Muruganandam M, Jan I, Harji F M, Harrington J, Konstantinov K N

机构信息

1Department of Medicine, Division of Rheumatology, University of New Mexico School of Medicine, Albuquerque, NM 87131 USA.

Section of Rheumatology, Raymond G. Murphy Veterans Affairs Medical Center, 1501 San Pedro SE, Albuquerque, NM 87108 USA.

出版信息

Auto Immun Highlights. 2019 Sep 17;10(1):8. doi: 10.1186/s13317-019-0118-4. eCollection 2019 Dec.

Abstract

Granulomatosis with polyangiitis (GPA) is a systemic vasculitis with a potential to involve any organ system. It remains an important cause of kidney related morbidity and mortality. Early diagnosis can be difficult and requires high index of suspicion in all patients, but especially in cases with atypical presentation. We report a case with GPA, which was diagnosed only after new and advancing symptoms belied the original diagnosis of bilateral facial palsy and aortic mural thrombus.

摘要

肉芽肿性多血管炎(GPA)是一种可累及任何器官系统的系统性血管炎。它仍然是导致肾脏相关发病和死亡的重要原因。早期诊断可能困难,需要对所有患者,尤其是表现不典型的病例保持高度怀疑。我们报告一例GPA病例,该病例仅在新出现和进展性症状与最初诊断的双侧面神经麻痹和主动脉壁血栓不符后才得以确诊。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdb6/7065353/ca8410dd1d78/13317_2019_118_Fig1_HTML.jpg

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