Rousslang Nikki D, Rooks Elizabeth, Delaney Kara
Department of Medical Education, University of Hawaii John A. Burns School of Medicine, Hawaii.
Department of Radiology, Tripler Army Medical Center, Honolulu, Hawaii.
J Clin Imaging Sci. 2020 Mar 31;10:13. doi: 10.25259/JCIS_168_2019. eCollection 2020.
Wilms tumor (nephroblastoma) is the most common renal malignancy of childhood and typically presents as a painless abdominal mass. The high success rates of surgery and chemotherapy make recurrence of Wilms tumor uncommon. We report the case of a 5-year-old girl who underwent radical nephrectomy and chemotherapy for a Wilms tumor, but suffered a relapse of the tumor to the lung. The metastasis was initially detected as a density on chest radiograph that was, coincidentally, in the same location as a recently explanted chest port. The diagnosis of recurrent malignancy was thus obscured by the patient's history as well as a correlating physical examination finding of a palpable mass at the site of the previously placed chest port. Moreover, the mass was not seen on lateral view, all of which suggested an alternative diagnosis of granulation tissue versus seroma rather than recurrent Wilms tumor. A high degree of clinical suspicion was necessary on the part of the clinician and radiologist to diagnose the relapse.
肾母细胞瘤是儿童期最常见的肾脏恶性肿瘤,通常表现为无痛性腹部肿块。手术和化疗的高成功率使得肾母细胞瘤复发并不常见。我们报告了一例5岁女孩的病例,她因肾母细胞瘤接受了根治性肾切除术和化疗,但肿瘤复发转移至肺部。转移灶最初在胸部X线片上被检测为密度影,巧合的是,其位置与最近取出的胸部端口相同。因此,患者的病史以及在先前放置胸部端口的部位可触及肿块这一相关体格检查结果掩盖了复发性恶性肿瘤的诊断。此外,侧位片上未见肿块,所有这些都提示诊断为肉芽组织或血清肿而非肾母细胞瘤复发。临床医生和放射科医生需要高度的临床怀疑才能诊断出复发情况。