Kagawa Yosuke, Kitaguchi Soichi, Konishi Hanae, Hashimoto Kaori, Norihito Osaki, Mizumoto Tadashi, Nishino Ryohei, Sugahara Fumihiro
Department of Respiratory Medicine, Hiroshima City Asa Citizens Hospital, 2-1-1 Kabe-Minami, Asa-kita-ku, Hiroshima, 731-0293 Japan.
Int Cancer Conf J. 2020 Feb 14;9(2):72-76. doi: 10.1007/s13691-020-00399-2. eCollection 2020 Apr.
A 61-year-old woman was referred to our hospital due to right chest pain. A huge, 13-cm-diameter tumor was detected in the right lower lobe. For diagnostic and treatment purposes, pneumonectomy was performed, and the tumor was diagnosed as advanced pulmonary synovial sarcoma (SS) with pleural metastasis, according to immunohistochemistry analysis. Due to recurrence with brain metastases, treatment sequence composed of radiosurgery, doxorubicin, eribulin, and pazopanib was selected. The patient died after a considerably long survival of 29 months after the first visit. This case suggests that multimodal treatment may provide prolonged survival even for patients with advanced SS.
一名61岁女性因右胸痛被转诊至我院。在右下叶发现一个直径达13厘米的巨大肿瘤。出于诊断和治疗目的，实施了肺切除术，根据免疫组化分析，该肿瘤被诊断为伴有胸膜转移的晚期肺滑膜肉瘤（SS）。由于出现脑转移复发，选择了由立体定向放射外科、多柔比星、艾日布林和帕唑帕尼组成的治疗方案。患者在首次就诊后存活了相当长的29个月后死亡。该病例表明，即使对于晚期SS患者，多模式治疗也可能延长生存期。
