Dolz-Planas M, González-Rodriguez F, Belda-Maximino R, Herraez-Dominguez J V
Department of Physics, Valencia University, Faculty of Pharmacy, Spain.
J Pharm Sci. 1988 Sep;77(9):799-801. doi: 10.1002/jps.2600770917.
An extensive study has been made of the thixotropic behavior of a microcrystalline cellulose-sodium carboxymethylcellulose gel (2% weight) and of its modification due to physical factors such as agitation time, duration of storage at rest, and temperature. An empirical function, giving thixotropic area variation rate as a function of agitation time, was obtained and found to be practically independent of storage time.