Ena Pasquale, Ena Luca, Ferrari Marco, Sotgiu M Alessandra, Mazzarello Vittorio
Skinlab, Department of Biomedical Sciences, University of Sassari, Sassari, Italy.
Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.
JAAD Case Rep. 2020 Mar 26;6(4):365-368. doi: 10.1016/j.jdcr.2020.02.008. eCollection 2020 Apr.
Double little toenails, or accessory nails of the fifth toe, are a rare and particular deformity distinct from other nail dysplasias. We describe 4 cases of female patients, including a 6-year-old girl, experiencing this bilateral condition after birth. The nail anomaly shows an autosomal-dominant type of transmission that affects only female individuals. The subjects examined were from a family without marriages between blood relatives and without neuroectodermal hereditary diseases. The 4 patients had no bone alterations of the terminal phalanges of the fifth toe or alterations of the joints of the toes or hair. One patient had nail deformity associated with epilepsy; another patient, associated with an infection of an accessory nail.
复发性小趾甲，即第五趾副甲，是一种罕见且特殊的畸形，与其他指甲发育异常不同。我们描述了4例女性患者，包括一名6岁女孩，她们出生后均出现这种双侧病症。这种指甲异常表现为常染色体显性遗传，仅影响女性个体。所检查的对象来自一个无近亲结婚且无神经外胚层遗传性疾病的家庭。这4例患者的第五趾末节指骨无骨质改变，脚趾关节及毛发也无异常。1例患者的指甲畸形与癫痫有关；另1例患者与副甲感染有关。
