Silva Mariana, Godinho Ana, Freitas João
Universidade do Porto, Faculdade de Medicina, Porto, Portugal.
Centro Hospitalar São João, Cardiologia, Porto, Portugal.
Porto Biomed J. 2016 Jul-Aug;1(3):118-123. doi: 10.1016/j.pbj.2016.07.001. Epub 2016 Aug 25.
Transient loss of consciousness (TLoC) is a symptom that has several differential etiologic diagnosis, causes significant morbidity and mortality with impact on quality of life.
The purpose of this study was to access the diagnosis and prognosis of these patients admitted in a Portuguese University Hospital.
The study included 125 patients with TLoC admitted in the emergency room and then admitted to the hospital during the year 2013. Patients were contacted by phone for follow-up evaluations, during the 18 months from the date of admission.
Cardiogenic syncope was the most common etiology of TLoC (39.2%). The 18-month overall mortality was 11.2%, however this was higher in patients with unexplained TLoC, with an 18-month mortality of 27.8% ( = 0.031); It was found that half of patients who died, did so in the first month from admission date; 20% of patients had recurrent episodes of TLoC (mean number of 5.6 episodes), with a higher percentage of recurrence occurring in patients with reflex syncope (35.3%; = 0.023). 60% of patients with recurrent episodes suffered accidents and/or injuries, and 20% of recurrence patients gave up driving ( = 0.019).
The results obtained highlight the burden of TLoC in terms of morbidity and mortality, similar results to those previously published, except for the prevalence of the etiology, cause of death and recurrence's etiology of TLoC. This study emphasizes the significant implications that TLoC leads on morbidity and mortality being essential its accurate diagnosis.
短暂性意识丧失(TLoC)是一种具有多种鉴别病因诊断的症状,会导致显著的发病率和死亡率,并对生活质量产生影响。
本研究的目的是评估在一家葡萄牙大学医院住院的这些患者的诊断和预后。
该研究纳入了2013年期间在急诊室就诊并随后入院的125例TLoC患者。在入院日期后的18个月内,通过电话联系患者进行随访评估。
心源性晕厥是TLoC最常见的病因(39.2%)。18个月的总死亡率为11.2%,然而,不明原因TLoC患者的死亡率更高,18个月死亡率为27.8%(P = 0.031);发现一半的死亡患者在入院后的第一个月内死亡;20%的患者有TLoC复发发作(平均发作次数为5.6次),反射性晕厥患者的复发率更高(35.3%;P = 0.023)。60%的复发患者发生了事故和/或受伤,20%的复发患者放弃了驾驶(P = 0.019)。
所获得的结果突出了TLoC在发病率和死亡率方面的负担,与先前发表的结果相似,除了TLoC的病因患病率、死亡原因和复发病因。本研究强调了TLoC对发病率和死亡率的重大影响,准确诊断至关重要。