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Pyruvate Dehydrogenase Kinase 4: A Key Mediator for Metabolic Regulation of Liver Regeneration.

作者信息

Burdick James, Sun Zhaoli

机构信息

Department of Surgery Johns Hopkins University School of Medicine Baltimore MD.

出版信息

Hepatol Commun. 2020 Mar 31;4(4):475-477. doi: 10.1002/hep4.1506. eCollection 2020 Apr.

DOI:10.1002/hep4.1506
PMID:32258943
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7109337/
Abstract
摘要

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本文引用的文献

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PDK4-Deficiency Reprograms Intrahepatic Glucose and Lipid Metabolism to Facilitate Liver Regeneration in Mice.丙酮酸脱氢酶激酶4缺乏可重编程肝内葡萄糖和脂质代谢以促进小鼠肝脏再生。
Hepatol Commun. 2020 Feb 5;4(4):504-517. doi: 10.1002/hep4.1484. eCollection 2020 Apr.
2
Small for Size and Flow (SFSF) syndrome: An alternative description for posthepatectomy liver failure.小肝综合征和小肝流出量（SFSF）：肝切除术后肝功能衰竭的另一种描述。
Clin Res Hepatol Gastroenterol. 2016 Jun;40(3):267-275. doi: 10.1016/j.clinre.2015.06.024. Epub 2015 Oct 26.
3
Interleukin-6 is required for cell cycle arrest and activation of DNA repair enzymes after partial hepatectomy in mice.白细胞介素-6 是小鼠肝部分切除后细胞周期停滞和激活 DNA 修复酶所必需的。
Cell Biosci. 2014 Feb 3;4(1):6. doi: 10.1186/2045-3701-4-6.
4
Elucidating the metabolic regulation of liver regeneration.阐明肝脏再生的代谢调控。
Am J Pathol. 2014 Feb;184(2):309-21. doi: 10.1016/j.ajpath.2013.04.034. Epub 2013 Oct 17.
5
Liver regeneration is impaired in lipodystrophic fatty liver dystrophy mice.脂肪营养不良性脂肪肝营养不良小鼠的肝再生受损。
Hepatology. 2010 Dec;52(6):2109-17. doi: 10.1002/hep.23920. Epub 2010 Oct 21.
6
Focal liver necrosis appears early after partial hepatectomy and is dependent on T cells and antigen delivery from the gut.局灶性肝坏死在部分肝切除术后早期出现，且依赖于T细胞和来自肠道的抗原传递。
Liver Int. 2009 Sep;29(8):1273-84. doi: 10.1111/j.1478-3231.2009.02048.x. Epub 2009 Jun 16.
7
Pyruvate dehydrogenase kinase-4 deficiency lowers blood glucose and improves glucose tolerance in diet-induced obese mice.丙酮酸脱氢酶激酶4缺乏可降低饮食诱导的肥胖小鼠的血糖并改善其糖耐量。
Am J Physiol Endocrinol Metab. 2008 Jul;295(1):E46-54. doi: 10.1152/ajpendo.00536.2007. Epub 2008 Apr 22.