Dardenne M, Clot J, Michel F B
Ann Immunol (Paris). 1977 Jan-Mar;128(1-2):71-2.
We have investigated lymphocyte subpopulations and T cell functions, in particular E rosettes and serum level of thymic factor in ten young patients (aged 6 to 20) with partial and selective IgA deficiency. The control group included ten age-matched healthy subjects. Significantly depressed levels of serum thymic factor were found in six patients. These results were correlated with the decreased number of E rosettes found in five of them, and support a T-cell involvement in IgA deficiency.
我们研究了10例部分性和选择性IgA缺乏的年轻患者（年龄6至20岁）的淋巴细胞亚群和T细胞功能，特别是E玫瑰花结和胸腺因子血清水平。对照组包括10名年龄匹配的健康受试者。6例患者血清胸腺因子水平显著降低。这些结果与其中5例患者E玫瑰花结数量减少相关，支持T细胞参与IgA缺乏。
