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酮咯酸罕见的副作用——过敏反应:一例报告

Anaphylaxis as a Rare Side Effect of Ketorolac; a Case Report.

作者信息

Yousefi Hesam, Sahebi Ali, Farahani Mahtab, Golitaleb Mohamad

机构信息

Department of Pharmaceutical Care, Sajad Hospital, Kermanshah, Iran.

Clinical Research Development Unit, Shahid Mostafa Khomeini Hospital, Ilam University of Medical Sciences, Ilam, Iran.

出版信息

Arch Acad Emerg Med. 2020 Mar 17;8(1):e22. eCollection 2020.

PMID:32259118
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7130438/
Abstract

Anaphylaxis is a life-threatening systemic allergic hypersensitivity reaction that may potentially be triggered after the administration of any drug. Our case was a 51-year-old man with the history of mild pain in his flanks since the night before he was admitted to our hospital. The patient was diagnosed with urolithiasis and admitted to the emergency department. He developed anaphylaxis after intravenous injection of 30 mg ketorolac. Allergic reactions to non-steroidal anti-inflammatory drugs (NSAIDs) such as ketorolac are rare; nonetheless, they can be life-threatening and should be carefully monitored.

摘要

过敏反应是一种危及生命的全身性过敏性超敏反应,在使用任何药物后都有可能引发。我们的病例是一名51岁男性,自入院前一晚起双侧胁腹有轻度疼痛病史。该患者被诊断为尿石症并入住急诊科。他在静脉注射30毫克酮咯酸后发生了过敏反应。对酮咯酸等非甾体抗炎药(NSAIDs)的过敏反应很少见;尽管如此,它们可能危及生命,应仔细监测。

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Non-steroidal anti-inflammatory drug effects on renal and cardiovascular function: from physiology to clinical practice.非甾体抗炎药对肾脏和心血管功能的影响:从生理学到临床实践
Eur J Prev Cardiol. 2020 May;27(8):850-867. doi: 10.1177/2047487319848105. Epub 2019 May 14.
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Pharmacokinetics of ketorolac in wild Eastern box turtles (Terrapene carolina carolina) after single intramuscular administration.单次肌肉注射后酮咯酸在野生东部箱龟(卡罗莱纳箱龟指名亚种)体内的药代动力学
J Vet Pharmacol Ther. 2019 Mar;42(2):154-159. doi: 10.1111/jvp.12733. Epub 2018 Nov 4.
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Anaphylaxis as a Rare Side Effect of Pantoprazole; a Case Report.泮托拉唑罕见副作用引发过敏反应;病例报告
Emerg (Tehran). 2018;6(1):e34. Epub 2018 May 21.
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Korean J Anesthesiol. 2010 Jun;58(6):565-8. doi: 10.4097/kjae.2010.58.6.565. Epub 2010 Jun 23.
5
Death due to anaphylactic shock secondary to intravenous self-injection of Toradol: a case report and review of the literature.因静脉内自行注射托拉朵尔继发过敏性休克死亡:一例病例报告及文献复习
Clin Toxicol (Phila). 2007 Sep;45(6):709-13. doi: 10.1080/15563650701397076.
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Report of an anaphylactoid and an anaphylactic reaction to ketorolac in two pediatric surgical patients.两名小儿外科患者对酮咯酸发生类过敏反应和过敏反应的报告。
Ther Drug Monit. 2006 Jun;28(3):458-62. doi: 10.1097/01.ftd.0000196661.97607.d4.
7
Selective severe anaphylactic reaction due to ketorolac tromethamine without nonsteroidal anti-inflammatory drug intolerance.因酮咯酸氨丁三醇导致的选择性严重过敏反应,无非甾体抗炎药不耐受情况。
J Allergy Clin Immunol. 2001 Mar;107(3):557. doi: 10.1067/mai.2001.113241.