Allergy Centre, Tampere University Hospital, Tampere, Finland.
Pediatric Research Centre, Tampere University, Tampere, Finland.
Acta Paediatr. 2020 Aug;109(8):1620-1626. doi: 10.1111/apa.15288. Epub 2020 Apr 23.
Paediatric asthma hospitalisation has decreased in Finland, but has remained stable in Sweden. The reasons for these intercountry differences are unclear. The aim of this study was to explore the trend of dispensed asthma medication, including inhaled corticosteroids (ICS), among paediatric populations in the two countries.
We explored trends in dispensed asthma medication among paediatric populations aged 0-19 in Finland and Sweden from 2006 to 2017. The Finnish Statistics on Reimbursements for Prescription Medicines and The Swedish Prescribed Drug Register provided data on all dispensed asthma prescriptions.
During the study period, the prevalence of dispensed ICS in paediatric populations was fairly stable in Finland and Sweden. Among children aged 0-4, ICS were 1.5 times more commonly dispensed in Sweden than in Finland. The prevalence of children dispensed short-acting beta-2 adrenergic receptor agonists (SABA) increased in both countries, but rose more in Finland (51%) than in Sweden (27%).
Inhaled corticosteroids were more commonly dispensed for children aged 0-4 in Sweden than in Finland during the study period. This study showed an increasing prevalence of children dispensed SABA in Finland and Sweden, particularly in Finland. Differences and trends in asthma medication may effect asthma hospitalisation and asthma deaths.
芬兰的儿科哮喘住院率下降,但瑞典保持稳定。造成这些国家间差异的原因尚不清楚。本研究旨在探讨两国儿科人群中开具的哮喘药物(包括吸入性皮质类固醇)的趋势。
我们探讨了 2006 年至 2017 年芬兰和瑞典 0-19 岁儿科人群中开具的哮喘药物的趋势。芬兰的《报销处方药统计》和《瑞典处方药登记册》提供了所有开具的哮喘处方的数据。
在研究期间,芬兰和瑞典儿科人群中开具的 ICS 流行率相当稳定。0-4 岁儿童中,瑞典开具 ICS 的比例是芬兰的 1.5 倍。两国中,短期β2 受体激动剂(SABA)的儿童使用率均有所增加,但芬兰(51%)的增幅高于瑞典(27%)。
在研究期间,瑞典 0-4 岁儿童开具 ICS 的比例高于芬兰。本研究显示,芬兰和瑞典开具 SABA 的儿童比例均有所增加,尤其是芬兰。哮喘药物的差异和趋势可能会影响哮喘住院率和哮喘死亡率。