Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Diagn Cytopathol. 2020 Jul;48(7):675-678. doi: 10.1002/dc.24423. Epub 2020 Apr 7.
Lymphatic filariasis is a major public health problem in the developing countries. In India, around 90% of the cases are attributed to Wuchereria bancrofti species morphologically identified as sheathed parasites with tail tip free of nuclei. Microfilariae have been described in urine specimens from patients with chylous and achylous hematuria as well as in a spectrum of other body fluids. Case reports describe their presence in aspirates from numerous neoplasms. However, their association with urothelial carcinoma in urine sediment has been rather rare with only three cases described previously. We report three cases of filariasis in urine cytology, one of which was associated with atypical urothelial cells. Our aim is to stress on the possibility of concomitant filariasis in body fluids and aspirates with other significant findings, especially in endemic areas. Identification of the same renders complete diagnosis and proper treatment to the patient.
淋巴丝虫病是发展中国家的一个主要公共卫生问题。在印度，约 90%的病例归因于形态学上被鉴定为有鞘寄生虫的班氏吴策线虫物种，其尾端无核。微丝蚴已在乳糜血尿和非乳糜血尿患者的尿液标本以及一系列其他体液中被描述。病例报告描述了它们在来自许多肿瘤的抽吸物中的存在。然而，它们与尿液沉淀物中的尿路上皮癌的关联相当罕见，以前仅描述了三例。我们报告了三例尿液细胞学中的丝虫病，其中一例与非典型尿路上皮细胞有关。我们的目的是强调在有其他重要发现的体液和抽吸物中同时存在丝虫病的可能性，特别是在流行地区。识别出相同的寄生虫可以为患者提供完整的诊断和适当的治疗。
