Ju Qiang, Campbell Paul S, Mudring Anja-Verena
Inorganic Chemistry III - Materials Engineering and Characterization, Fakultät fur Chemie und Biochemie, Ruhr-Univerisität Bochum, D-44780 Bochum, Germany.
J Mater Chem B. 2013 Jan 14;1(2):179-185. doi: 10.1039/c2tb00052k. Epub 2012 Oct 22.
Phase-selective synthesis of trivalent lanthanide-doped NaGdF nanocrystals, capped by ionic liquid cations bearing long alkyl chains, succeeded via a one-step interface-assisted ionothermal route. Owing to the existence of an interface formed between hydrophobic ionic liquids and ethylene glycol, selectively either pure cubic or hexagonal phase NaGdF could be obtained by changing the amount of the added surfactant, polyethyleneimine. By doping various trivalent lanthanide cations, multicolor emissions under excitation by a single wavelength could be achieved. The nanocrystals can be surface derivatized by an amphiphilic polymer and endowed with functional groups that allow the particles to not only be dispersed in aqueous solutions but also present biocompatibility. After conjugation with biotin, the nanocrystals could be used for time-resolved fluorescence resonance energy transfer biodetection.
通过一步界面辅助离子热法成功实现了由带有长烷基链的离子液体阳离子封端的三价镧系元素掺杂的NaGdF纳米晶体的相选择性合成。由于在疏水性离子液体和乙二醇之间形成了界面，通过改变添加的表面活性剂聚乙烯亚胺的量，可以选择性地获得纯立方相或六方相的NaGdF。通过掺杂各种三价镧系阳离子，可以在单波长激发下实现多色发射。纳米晶体可以用两亲聚合物进行表面衍生化，并赋予其官能团，使颗粒不仅能够分散在水溶液中，还具有生物相容性。与生物素缀合后，纳米晶体可用于时间分辨荧光共振能量转移生物检测。
