Vetrova E G, Drozdova T E, Popova I A
Kosm Biol Aviakosm Med. 1988 Jul-Aug;22(4):70-3.
Seven-day exposure to clinostatic and antiorthostatic hypokinesia led to a significant decrease of Krebs cycle enxymes (malate dehydrogenase--MDH and isocitrate dehydrogenase) and creatine phosphokinase with no significant changes in lactate dehydrogenase (LDH), aspartate aminotransferase, alanine aminotransferase and MDH and LDH isoenzymes. This hypofermentemia returned to normal during 7-day readaptation. It was not associated with hemodynamic changes or emotional stress. The hypofermentemia was adaptive and induced by diminished motor activity.
为期七天的卧床及头低位静止性低动力状态暴露导致三羧酸循环酶(苹果酸脱氢酶——MDH和异柠檬酸脱氢酶)和肌酸磷酸激酶显著减少,而乳酸脱氢酶(LDH)、天冬氨酸氨基转移酶、丙氨酸氨基转移酶以及MDH和LDH同工酶无显著变化。这种酶减少血症在为期七天的重新适应过程中恢复正常。它与血液动力学变化或情绪应激无关。酶减少血症具有适应性,是由运动活动减少所致。