Williams R D, Fisher F W
Arch Surg. 1977 Apr;112(4):415-6. doi: 10.1001/archsurg.1977.01370040067010.
During the past 5 1/2 years, cultures were taken from 68 to 151 surgically treated aortic aneurysms. These cultures were made from nonblood fluids, laminated clot, necrotic areas of the aneurysm wall, or ulcerated atheromatous plaques. Organisms were harvested from seven of the 68 cultures, including Staphylococcus, Escherichia coli, Pseudomonas, and hemolytic Streptococcus. Prophylactic antibiotics were used in all patients; however, the organisms cultured, excepting Streptococcus, were not sensitive to the chosen antibiotics. Three of the seven patients with a positive aneurysm culture died of causes unrelated to infection. Evidence of graft infection has not developed in four surviving patients with positive cultures. Knowledge of the presence of bacteria permitted massive antibiotic therapy based on organism sensitivity.
在过去的5年半时间里，从68至151个接受手术治疗的主动脉瘤中采集了样本进行培养。这些样本取自非血液液体、层状血栓、动脉瘤壁的坏死区域或溃疡的动脉粥样硬化斑块。从68个培养样本中的7个分离出了微生物，包括葡萄球菌、大肠杆菌、假单胞菌和溶血性链球菌。所有患者均使用了预防性抗生素；然而，除链球菌外，培养出的微生物对所选抗生素不敏感。7例动脉瘤培养呈阳性的患者中有3例死于与感染无关的原因。4例培养呈阳性的存活患者未出现移植物感染的迹象。了解细菌的存在使得能够根据微生物敏感性进行大规模抗生素治疗。
