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通过静电纺丝丝纤维束的机电驱动来模拟肌肉纤维的结构和功能。

Mimicking muscle fiber structure and function through electromechanical actuation of electrospun silk fiber bundles.

作者信息

Severt S Y, Maxwell S L, Bontrager J S, Leger J M, Murphy A R

机构信息

Department of Chemistry, Western Washington University, 516 High St., Bellingham, WA 98225, USA.

出版信息

J Mater Chem B. 2017 Oct 28;5(40):8105-8114. doi: 10.1039/c7tb01904a. Epub 2017 Oct 4.

DOI:10.1039/c7tb01904a
PMID:32264649
Abstract

Here we detail the fabrication and testing of artificial muscles fabricated from composites of the natural biopolymer silk fibroin and conducting polymers. Aligned nanofiber bundles of silk that mimic the structure of skeletal muscles were produced via electrospinning, and the fibers were infused with conducting polymers using chemical and electrochemical in situ polymerization methods. The resulting bundles of individual, electroactive fibers underwent electromechanical actuation in biologically-relevant electrolyte solutions when low potentials were applied, thus mimicking the contractile function of native muscles. The fabrication methods, bulk mechanical properties, stress and strain generation, and stability under repeated actuation for fiber bundles coated with different conducting polymer formulations are presented.

摘要

在此,我们详细介绍了由天然生物聚合物丝素蛋白与导电聚合物的复合材料制成的人造肌肉的制造与测试过程。通过静电纺丝制备出模仿骨骼肌结构的丝素蛋白排列纳米纤维束,并采用化学和电化学原位聚合方法将导电聚合物注入纤维中。当施加低电势时,由此产生的单个电活性纤维束在与生物相关的电解质溶液中会发生机电驱动,从而模拟天然肌肉的收缩功能。本文还介绍了不同导电聚合物配方涂层纤维束的制造方法、整体力学性能、应力和应变产生情况以及反复驱动下的稳定性。

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