碘帕醇腰椎脊髓造影：副作用调查的一种方法学途径。
Lumbar myelography with iopamidol: a methodological approach to the investigation of side effects.
作者信息
Provinciali L, Signorino M, Giovagnoli A R, Baroni M, Angeleri F, Salvolini U, Pasquini U, Porta M, Judice A, Cerutti R
机构信息
Institute of Nervous System Diseases, University of Ancona, Italy.
出版信息
Neuroradiology. 1988;30(6):528-33. doi: 10.1007/BF00339695.
Pathophysiology of adverse reactions occurring during myelography with non-ionic contrast agents, such as iopamidol, seem related to their direct action on the nervous system. The authors try a multivariate approach, involving neurophysiological, neuropsychological and neurochemical parameters on a pilot group of twelve subjects. Any possible change in the above examinations is thoroughly analyzed and correlated to the postulated neurotoxic properties of contrast media.
使用非离子型造影剂（如碘帕醇）进行脊髓造影时发生不良反应的病理生理学，似乎与其对神经系统的直接作用有关。作者尝试采用多变量方法，对12名受试者的试验组进行神经生理学、神经心理学和神经化学参数研究。对上述检查中任何可能的变化进行了全面分析，并将其与造影剂假定的神经毒性特性相关联。
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