Instituto de Previsión Social, Hospital Central, Asunción, Paraguay.
Centro de Estudios Económicos y Sociales en Salud, Universidad San Ignacio de Loyola, Lima, Perú.
Climacteric. 2020 Dec;23(6):566-573. doi: 10.1080/13697137.2020.1742684. Epub 2020 Apr 8.
Depressive symptoms may affect female mid-life sexuality, whereas sexual problems tend to aggravate depression. Despite this, data assessing this association drawn from mid-aged Paraguayan women are scarce.
This study aimed to assess the association between depressed mood and the risk of sexual dysfunction during female mid-life.
Sexually active urban-living women from Asunción, Paraguay ( = 193, aged 40-60 years) were surveyed with the 6-item Female Sexual Function Index (FSFI-6), the 10-item Center for Epidemiological Studies Depression Scale (CESD-10), and a general questionnaire containing personal and partner information. Depressed mood was defined as a total CESD-10 score of 10 or more, and an increased risk for sexual dysfunction as an FSFI-6 total score of 19 or less. The association of depressed mood and an increased risk of sexual dysfunction was evaluated with multivariable Poisson regression.
The mean age (±standard deviation) of surveyed woman was 48.3 ± 6.0 years and 61.1% ( = 118) were perimenopausal and postmenopausal. A total of 21.8% ( = 42) had depressed mood and 28.5% ( = 55) had an increased risk of sexual dysfunction. The final adjusted regression model determined that women with depressed mood were twice as likely to have an increased risk of sexual dysfunction, compared to women with normal mood (adjusted prevalence ratio = 2.14, 95% confidence interval 1.26-3.60). On the other hand, depressed mood was associated with a mean total FSFI-6 score that was 20% lower than that observed among women with normal mood (adjusted incidence rate ratio = 0.80, 95% confidence interval 0.68-0.93).
In this mid-aged Paraguayan female sample there was a significant association between depressed mood and an increased risk of sexual dysfunction.
抑郁症状可能会影响女性中年期的性生活，而性生活问题往往会加重抑郁。尽管如此，从中年巴拉圭女性中得出的评估这种关联的数据仍然很少。
本研究旨在评估女性中年期抑郁情绪与性功能障碍风险之间的关系。
对来自巴拉圭亚松森的城市活跃女性（n=193，年龄 40-60 岁）进行了调查，使用 6 项女性性功能指数（FSFI-6）、10 项流行病学研究抑郁量表（CESD-10）和一份包含个人和伴侣信息的一般问卷。抑郁情绪定义为 CESD-10 总分 10 分或以上，性功能障碍风险增加定义为 FSFI-6 总分 19 分或以下。使用多变量泊松回归评估抑郁情绪与性功能障碍风险增加之间的关系。
被调查女性的平均年龄（±标准差）为 48.3±6.0 岁，61.1%（n=118）处于围绝经期和绝经后期。共有 21.8%（n=42）有抑郁情绪，28.5%（n=55）有性功能障碍风险增加。最终调整后的回归模型确定，与情绪正常的女性相比，有抑郁情绪的女性发生性功能障碍风险增加的可能性是其两倍（调整后的患病率比=2.14，95%置信区间 1.26-3.60）。另一方面，抑郁情绪与 FSFI-6 总分平均降低 20%相关，而 FSFI-6 总分在情绪正常的女性中观察到（调整后的发病率比=0.80，95%置信区间 0.68-0.93）。
在这个中年巴拉圭女性样本中，抑郁情绪与性功能障碍风险增加之间存在显著关联。
