Lemmens Cynthia M C, Khalilzada Mostafa, Holleboom Caspar A G, Ramautar Sharita R, Hagenbeek Rogier E
Haaglanden Medisch Centrum, Den Haag. Afd. Neurologie.
Contact: Cynthia M.C. Lemmens (
Ned Tijdschr Geneeskd. 2020 Mar 5;164:D4274.
Sheehan's syndrome is a rare complication of excessive postpartum hemorrhage with impaired function of the pituitary gland (hypopituitarism). Clinical presentation includes headache, fatigue, nausea, symptoms due to electrolyte imbalance and pituitary hormone insufficiency. Cranial imaging can support the diagnosis if pituitary gland ischemia or empty sella sign is detected. Therapy is based on correction of hypovolemia in the acute setting, symptom reduction and chronic hormone replacement treatment.
We report a case of a patient who developed Sheehan's syndrome as a result of severe blood loss during cesarean section. Brain imaging in this case was initially performed with an alternative differential diagnosis in mind.
Differential diagnosis of headache in puerperium is comprised of a spectrum of syndromes, in which attention for medical and patient history are key. In Sheehan's syndrome early diagnosis is of crucial prognostic importance.
席汉综合征是产后大出血导致垂体功能受损(垂体功能减退)的一种罕见并发症。临床表现包括头痛、疲劳、恶心、电解质失衡和垂体激素不足引起的症状。如果检测到垂体缺血或空蝶鞍征,头颅影像学检查可支持诊断。治疗基于急性期纠正血容量不足、减轻症状以及慢性激素替代治疗。
我们报告一例患者,该患者因剖宫产术中严重失血而发生席汉综合征。该病例最初进行脑部成像时考虑的是其他鉴别诊断。
产褥期头痛的鉴别诊断包括一系列综合征,其中关注病史和患者病史是关键。在席汉综合征中,早期诊断对预后至关重要。