Division of Neonatology, Department of Pediatrics, Oishei Children's Hospital of Buffalo, University at Buffalo, Buffalo, New York.
Division of Neonatology, University and Polytechnic Hospital La Fe, Valencia, Spain.
Am J Perinatol. 2020 Jun;37(8):813-824. doi: 10.1055/s-0040-1709688. Epub 2020 Apr 8.
The first case of novel coronavirus disease of 2019 (COVID-19) caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) was reported in November2019. The rapid progression to a global pandemic of COVID-19 has had profound medical, social, and economic consequences. Pregnant women and newborns represent a vulnerable population. However, the precise impact of this novel virus on the fetus and neonate remains uncertain. Appropriate protection of health care workers and newly born infants during and after delivery by a COVID-19 mother is essential. There is some disagreement among expert organizations on an optimal approach based on resource availability, surge volume, and potential risk of transmission. The manuscript outlines the precautions and steps to be taken before, during, and after resuscitation of a newborn born to a COVID-19 mother, including three optional variations of current standards involving shared-decision making with parents for perinatal management, resuscitation of the newborn, disposition, nutrition, and postdischarge care. The availability of resources may also drive the application of these guidelines. More evidence and research are needed to assess the risk of vertical and horizontal transmission of SARS-CoV-2 and its impact on fetal and neonatal outcomes. KEY POINTS: · The risk of vertical transmission is unclear; transmission from family members/providers to neonates is possible.. · Optimal personal-protective-equipment (airborne vs. droplet/contact precautions) for providers is crucial to prevent transmission.. · Parents should be engaged in shared decision-making with options for rooming in, skin-to-skin contact, and breastfeeding..
首例 2019 年新型冠状病毒病(COVID-19)由严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)引起,于 2019 年 11 月报告。COVID-19 迅速发展为全球大流行,对医疗、社会和经济产生了深远的影响。孕妇和新生儿是弱势群体。然而,这种新型病毒对胎儿和新生儿的确切影响尚不确定。在 COVID-19 母亲分娩期间和分娩后,适当保护医护人员和新生儿至关重要。根据资源可用性、增长数量和潜在传播风险,各专家组织对最佳方法存在分歧。本文概述了对 COVID-19 母亲所生新生儿进行复苏前、复苏中和复苏后的预防措施和步骤,包括涉及与父母共同决策围产期管理、新生儿复苏、处置、营养和出院后护理的三种当前标准的可选变化。资源的可用性也可能推动这些指南的应用。需要更多的证据和研究来评估 SARS-CoV-2 的垂直和水平传播风险及其对胎儿和新生儿结局的影响。要点:
垂直传播的风险尚不清楚;家庭成员/提供者向新生儿传播是可能的。
提供人员最佳的个人防护设备(空气传播与飞沫/接触预防)对于预防传播至关重要。
应让父母参与共同决策,提供母婴同室、皮肤接触和母乳喂养的选择。