Pinc Jan, Čapek Jaroslav, Hybášek Vojtěch, Průša Filip, Hosová Klára, Maňák Jan, Vojtěch Dalibor
Department of Metals and Corrosion Engineering, University of Chemistry and Technology, 166 28 Prague, Czech Republic.
FZU-Institute of Physics of the Czech Academy of Sciences, 182 21 Prague, Czech Republic.
Materials (Basel). 2020 Apr 6;13(7):1716. doi: 10.3390/ma13071716.
Zinc and its alloys belong to a group of biodegradable materials, which can be potentially used for the preparation of temporary orthopedic implants. The research of biodegradable zinc materials revealed a lot of limitations; however, the new processing approaches of those materials can enhance their properties, which are insufficient for now. In this study, the zinc composite with 8 wt.% of hydroxyapatite (Zn/HA8) prepared for the first time by extrusion process was characterized from the point of view of the structural, mechanical and corrosion properties. The extrusion process led to good integrity of the interfaces between the zinc and hydroxyapatite particles. Mechanical behavior confirmed the role of hydroxyapatite as a defect in the material structure, which led to a decrease of the Zn/HA8 mechanical properties by approximately 30% (compressive yield strength (CYS) = 154 MPa Zn, 113 MPa Zn/HA8). Despite that, the Zn/HA8 composite showed sufficient mechanical properties for cancellous bone replacement and reached the lower limit for cortical bone. Additionally, the presence of hydroxyapatite caused the preferential precipitation of hydroxyapatite (HA) from the solution and can lead to a significant enhancement of the tissue/implant interface interactions.
锌及其合金属于一类可生物降解材料，可潜在地用于制备临时骨科植入物。对可生物降解锌材料的研究揭示了许多局限性；然而，这些材料的新加工方法可以增强其性能，目前这些性能还不够理想。在本研究中，首次通过挤压工艺制备的含8 wt.%羟基磷灰石的锌复合材料（Zn/HA8）从结构、力学和腐蚀性能的角度进行了表征。挤压工艺使锌与羟基磷灰石颗粒之间的界面具有良好的完整性。力学行为证实了羟基磷灰石在材料结构中作为缺陷的作用，这导致Zn/HA8的力学性能下降了约30%（抗压屈服强度（CYS）：锌为154 MPa，Zn/HA8为113 MPa）。尽管如此，Zn/HA8复合材料显示出足以替代松质骨的力学性能，并达到了皮质骨的下限。此外，羟基磷灰石的存在导致溶液中羟基磷灰石（HA）的优先沉淀，并可显著增强组织/植入物界面的相互作用。
