Zhang Y, Liu J Q, Zhang Q F, Sun Y J, Wang Y J, Xu D Y, Jin C, Li K Y
Department of Otorhinolaryngology, Renji hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China.
Institute of Micro/Nano Science and Technology, Shanghai Jiaotong University, Shanghai 200240, China.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Mar 7;55(3):236-240. doi: 10.3760/cma.j.issn.1673-0860.2020.03.009.
To investigate the effect of the artificial facial nerve on the restoration of orbicularis oculi muscle function for unilateral peripheral facial paralysis in rabbit. Artificial facial nerve was implanted into the rabbit with unilateral peripheral facial paralysis between January 2018 and May 2019. At different time points after operation, the affected orbicularis oculi muscles' stimulation closure threshold and the synchronism about the motion of the two sides of orbicularis oculi muscles were monitored. test was used with SPSS 13.0 software. There was no significant difference in the closure threshold of the orbicularis oculi muscle on the 7th and 28th days after artificial facial nerve implantation (0.05). The synchronism of the normal side eye closing movement triggered the affected orbicular oculi muscle movement with the artificial facial nerve was up 19/20 to 20/20 at different times. The artificial facial nerve system had the features of stable working condition and high synchronizing effect for stimulating movement. It could restore the closed eye function in animals with peripheral facial paralysis animals and had great clinical application prospects.
探讨人工面神经对兔单侧周围性面瘫眼轮匝肌功能恢复的影响。于2018年1月至2019年5月对单侧周围性面瘫兔植入人工面神经。术后不同时间点监测患侧眼轮匝肌的刺激闭合阈值及双侧眼轮匝肌运动的同步性。采用SPSS 13.0软件进行检验。人工面神经植入后第7天和第28天，眼轮匝肌的闭合阈值差异无统计学意义（P>0.05）。不同时间点，健侧闭眼运动触发患侧眼轮匝肌运动经人工面神经的同步率为19/20至20/20。人工面神经系统刺激运动具有工作状态稳定、同步效果好的特点。能恢复周围性面瘫动物的闭眼功能，具有较大的临床应用前景。
