Oxford Trauma, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), Kadoorie Centre, University of Oxford, Oxford, OX3 9DU, United Kingdom; Oxford University Hospitals NHS Foundation Trust, Trauma Research, Kadoorie Centre, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom.
Oxford Trauma, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), Kadoorie Centre, University of Oxford, Oxford, OX3 9DU, United Kingdom.
Injury. 2020 Jun;51(6):1331-1336. doi: 10.1016/j.injury.2020.03.031. Epub 2020 Mar 30.
Hip fractures are common in people over 60 years of age, and are associated with significant disability, morbidity and mortality. The aim of this study was to record the incidence of complications in the first 120 days following hip fracture.
The World Hip Trauma Evaluation (WHiTE) study is a multicentre, prospective cohort study conducted in National Health Service (NHS) hospitals in England and Wales. Participants are 60 years and older who received operative treatment for a hip fracture. We report the incidence of complications recorded by hospital staff until discharge from hospital and by participants at 120-days post-surgery.
An analysis of 8673 consecutive participants enrolled in the WHiTE study revealed the following risks of complications within the first 120 days: signs of wound infection (3.1%); dislocation (0.5%); failure of fixation (0.6%); peri‑prosthetic fracture (0.3%); overall revision surgery (0.9%); blood loss requiring transfusion (6.1%); chest infection (6.3%); urinary tract infection (5.0%); deep vein thrombosis/pulmonary embolus (1.8%); cerebrovascular accident (0.6%); acute coronary syndrome/myocardial infarction (0.6%); acute kidney injury (1.3%).
The rates of complications reported here provide a reference range against which future studies might be assessed. Registration: ISRCTN63982700.
髋部骨折在 60 岁以上人群中较为常见，与严重残疾、发病率和死亡率相关。本研究旨在记录髋部骨折后 120 天内的并发症发生率。
世界髋部创伤评估（WHiTE）研究是一项在英格兰和威尔士国民保健服务（NHS）医院进行的多中心、前瞻性队列研究。参与者为 60 岁及以上接受手术治疗的髋部骨折患者。我们报告了由医院工作人员记录的并发症发生率，直至患者出院，并报告了参与者术后 120 天的并发症发生率。
对 WHiTE 研究中连续纳入的 8673 名参与者进行分析，结果显示 120 天内的并发症风险如下：伤口感染迹象（3.1%）；脱位（0.5%）；固定失败（0.6%）；假体周围骨折（0.3%）；总体翻修手术（0.9%）；需要输血的失血（6.1%）；胸部感染（6.3%）；尿路感染（5.0%）；深静脉血栓形成/肺栓塞（1.8%）；脑血管意外（0.6%）；急性冠状动脉综合征/心肌梗死（0.6%）；急性肾损伤（1.3%）。
此处报告的并发症发生率为未来的研究提供了一个参考范围。注册：ISRCTN63982700。
