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减重手术的优先级:使用离散选择实验捕捉加拿大患者的偏好权重。

Prioritization for bariatric surgery: capturing Canadian patient preference weights using a discrete choice experiment.

机构信息

School of Pharmacy, Memorial University, St. John's, Newfoundland and Labrador, Canada.

Faculty of Medicine, Memorial University, St. John's, Newfoundland and Labrador, Canada.

出版信息

Surg Obes Relat Dis. 2020 Jun;16(6):751-759. doi: 10.1016/j.soard.2020.01.036. Epub 2020 Feb 11.

Abstract

BACKGROUND

Bariatric surgery is an effective treatment for adults affected by obesity. Demand is greater than supply and a prioritization system for patients is needed.

OBJECTIVE

Clinical practice guidelines recommends bariatric surgery as a management strategy for adults with severe obesity (body mass index ≥40 or 35-40 kg/m with co-morbidities). Eligible patient's access surgery on a first-come-first-serve basis and wait times can be several years. This study quantifies patient preferences toward attributes that could be evaluated when prioritizing patients for surgery.

SETTING

A Canada-wide study of adults living with obesity.

METHODS

A discrete choice experiment was conducted via email with a sample of Canadian adults with obesity. Six relevant attributes were identified through focus groups. Respondents completed 12 choice tasks and demographic and weight loss-related questions. A multinomial logit model was used to estimate preference weights of each attribute.

RESULTS

A total of 515 individuals completed the survey. Fifty-nine percent were female, 97% made previous weight loss attempts, and 5% had bariatric surgery. On average patients prioritized individuals with significant problems with daily activities versus none (odds ratio [OR] 4.41; 95% confidence interval [CI] 4.31-4.52); 3 existing cardiovascular co-morbidities versus 0 (OR 4.24; 95%CI 4.12-4.36); extreme impact on mental health versus no impact (OR 3.73; 95%CI 3.64-3.84); 6 other co-morbidities versus 0 (OR 3.43; 95%CI 3.31-3.55); waiting 5 versus 1 year (OR 1.59; 95%CI 1.46-1.68); and a body mass index of 60 versus 40 (OR 1.52; 95%CI 1.43-.62).

CONCLUSION

All 6 attributes were important to patients in the prioritization for bariatric surgery. However, the number of cardiovascular co-morbidities and the impact on daily activities were considered most important.

摘要

背景

减重手术是治疗肥胖成年人的有效方法。需求大于供应,因此需要为患者制定优先排序系统。

目的

临床实践指南建议将减重手术作为严重肥胖(体重指数≥40 或 35-40kg/m 伴有合并症)成年人的管理策略。符合条件的患者可先到先服务接受手术,等待时间可能长达数年。本研究量化了患者对可用于确定手术优先级的患者特征的偏好。

设置

一项针对加拿大肥胖成年人的全国性研究。

方法

通过电子邮件对加拿大肥胖成年人进行了一项离散选择实验。通过焦点小组确定了 6 个相关属性。受访者完成了 12 项选择任务以及人口统计学和减肥相关问题。使用多项逻辑回归模型来估计每个属性的偏好权重。

结果

共有 515 人完成了调查。59%为女性,97%曾尝试过减肥,5%接受过减重手术。平均而言,患者更倾向于选择那些日常生活有严重问题的人,而不是没有问题的人(优势比 [OR] 4.41;95%置信区间 [CI] 4.31-4.52);有 3 种现有心血管合并症的人比没有合并症的人(OR 4.24;95%CI 4.12-4.36);对心理健康的影响极大与无影响的人(OR 3.73;95%CI 3.64-3.84);有 6 种其他合并症的人比没有合并症的人(OR 3.43;95%CI 3.31-3.55);等待 5 年而不是 1 年(OR 1.59;95%CI 1.46-1.68);体重指数为 60 而不是 40(OR 1.52;95%CI 1.43-0.62)。

结论

在为减重手术进行优先级排序时,所有 6 个属性对患者都很重要。然而,心血管合并症的数量和对日常生活的影响被认为是最重要的。

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