Ormonde Carolina, Cabral Raquel, Serpa Sara
Nephrology Department, Hospital do Divino Espírito Santo, Ponta Delgada, Portugal.
Radiology Department, Hospital do Divino Espírito Santo, Ponta Delgada, Portugal.
Case Rep Nephrol. 2020 Mar 23;2020:3618763. doi: 10.1155/2020/3618763. eCollection 2020.
Osmotic demyelination syndrome (ODS) is characterized by loss of myelin in various parts of the central nervous system. It is mainly caused by a rapid correction of hyponatremia, although other factors that may cause rapid rise in serum osmolality can also be associated with its development. Its prognosis is poor and the recovery rate is unknown. The authors report a rare case of a patient with multiple risk factors for ODS, without hyponatremia, who developed ODS and surprisingly recovered. This case report highlights the importance of recognizing risk factors for the development of ODS, even if the main one is not present.
渗透性脱髓鞘综合征(ODS)的特征是中枢神经系统各部位的髓鞘丧失。它主要由低钠血症的快速纠正引起,尽管其他可能导致血清渗透压快速升高的因素也可能与其发生有关。其预后较差,恢复率未知。作者报告了一例罕见病例,该患者有发生ODS的多种危险因素,无低钠血症,却发生了ODS且令人惊讶地康复了。本病例报告强调了识别ODS发生危险因素的重要性,即使主要危险因素不存在。