Fatal refractory cardiac arrest as presentation of systemic amyloidosis.

作者信息

Chung Peter, Wheeler Sarah, Fong Andrew, Hurth Kyle, Yaghmour Bassam

机构信息

Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Keck School of Medicine at the University of Southern California, Los Angeles, CA, USA.

Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.

出版信息

Respir Med Case Rep. 2020 Mar 27;30:101042. doi: 10.1016/j.rmcr.2020.101042. eCollection 2020.

DOI:10.1016/j.rmcr.2020.101042

PMID:32274327

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7132166/

Abstract

Amyloidosis is a challenging diagnosis in the absence of clinical suspicion. The two patients reported here lacked any symptoms suggestive of amyloidosis. Instead, they presented with sudden, unexplained cardiac arrests that were persistent, treatment refractory, and ultimately fatal. Post-mortem examination unexpectedly revealed evidence of diffuse, systemic amyloidosis throughout multiple organ systems. We bring awareness to this unusual presentation of systemic amyloidosis that portends to poor outcome.

摘要