严重神经系统疾病患者喂养不耐受与不良预后的相关性：病例对照研究。
The correlation between feeding intolerance and poor prognosis of patients with severe neurological conditions: a case-control study.
机构信息
Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
出版信息
Expert Rev Neurother. 2020 May;20(5):415-416. doi: 10.1080/14737175.2020.1750372. Epub 2020 Apr 10.
BACKGROUND
This study aims to investigate the current status of feeding intolerance (FI) among patients with severe neurological conditions and to further determine the correlation between FI and their poor prognosis.
METHODS
This study performed a retrospective analysis of the medical data of 58 patients from January 2017 and December 2017. Patients were divided into two groups according to modified Rankin Scale (mRS) scores. Logistic regression was used to analyze the relevant factors for the poor prognosis of these patients.
RESULTS
General data analysis showed that age and diagnosis(stroke) were significantly different between the two groups ( < 005). Univariate analysis showed that APACHE II score, vomiting within 3 days of NICU admission, gastrointestinal bleeding within 3 days of NICU admission, and occurrence of FI within 3 days of NICU admission were all risk factors for a poor prognosis of these patients ( < 005). Multivariate logistic regression analysis showed that FI within 3 days of NICU admission (OR 8026, 95%CI (1550-26039)) and diagnosis (stroke) (OR 10654, 95%CI (1746-21291)) were independent factors for a poor prognosis of patients with severe neurological conditions.
CONCLUSION
The incidence of early FI in stroke patients is correlated with a poor prognosis.
背景
本研究旨在调查严重神经系统疾病患者喂养不耐受（FI）的现状，并进一步确定 FI 与预后不良之间的相关性。
方法
本研究对 2017 年 1 月至 2017 年 12 月的 58 例患者的医疗数据进行回顾性分析。根据改良 Rankin 量表（mRS）评分将患者分为两组。采用逻辑回归分析患者预后不良的相关因素。
结果
一般数据分析显示，两组间年龄和诊断（卒中）差异有统计学意义（ < 0.05）。单因素分析显示，APACHE II 评分、NICU 入院后 3 天内呕吐、NICU 入院后 3 天内胃肠道出血、NICU 入院后 3 天内发生 FI 均为患者预后不良的危险因素（ < 0.05）。多因素 logistic 回归分析显示，NICU 入院后 3 天内发生 FI（OR 8026，95%CI（1550-26039））和诊断（卒中）（OR 10654，95%CI（1746-21291））是严重神经系统疾病患者预后不良的独立因素。
结论
卒中患者早期 FI 的发生与预后不良相关。
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