Memorial Sloan Kettering Cancer Center, New York, NY.
MD Anderson Cancer Center, Houston, TX.
Blood. 2020 May 21;135(21):1829-1832. doi: 10.1182/blood.2020006028.
The International Lymphoma Radiation Oncology Group (ILROG) guidelines for using radiation therapy (RT) in hematological malignancies are widely used in many countries. The emergency situation created by the COVID-19 pandemic may result in limitations of treatment resources. Furthermore, in recognition of the need to also reduce the exposure of patients and staff to potential infection with COVID-19, the ILROG task force has made recommendations for alternative radiation treatment schemes. The emphasis is on maintaining clinical efficacy and safety by increasing the dose per fraction while reducing the number of daily treatments. The guidance is informed by adhering to acceptable radiobiological parameters and clinical tolerability. The options for delaying or omitting RT in some hematological categories are also discussed.
国际淋巴瘤放射肿瘤学组 (ILROG) 关于在血液恶性肿瘤中使用放射治疗 (RT) 的指南在许多国家得到广泛应用。COVID-19 大流行造成的紧急情况可能导致治疗资源受限。此外,为了减少患者和工作人员接触 COVID-19 潜在感染的风险,ILROG 工作组提出了替代放射治疗方案的建议。重点是通过增加每次分割的剂量,同时减少每日治疗次数,在保持临床疗效和安全性的同时,减少 RT 的应用。该指南遵循可接受的放射生物学参数和临床耐受性。还讨论了在某些血液学类别中延迟或省略 RT 的选择。